Hebei Nengqian Chemical Import and Export Co., LTD
Assessed Supplier
- Assessed
Supplier - 4th
years
Assessed Supplier
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: 86-139-10575315
Tel: +86 15632961819
Tel: +86 18233902561
Tel: +86 15717685612
Tel: +86 16630923639
Tel: +86 18732968538
Tel: +86 18833033983
Tel: +86 19831957301
Mobile: +86 19831957301
Tel: 86-139-10575315
Fax: 4001020630
URL: https://www.nengqianchemical.com/
Province/state: Hebei
City: Handan
Street: Congtai District, La Defense North
MaxCard:
Ms.AnnaCAS NO.129499-78-1
Pharmaceutical grade(1-50)KilogramPharmaceutical grade(51-99)Kilogram
Our Advantage
Rich Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.
Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.
24 hour service
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
| Ascorbyl glucoside Usage And Synthesis |
| Description | Ascorbyl glucoside is a natural active substance containing Vitamin C structure, but it is stable. Ascorbyl glucoside can effectively inhibit formation of melanin, dilute the skin color, reduce age spots and freckles pigmentation. Ascorbic Acid 2-Glucoside(AA-2G) was originally developed as a quasi-drug cosmetic product in Japan to lighten the overall tone of the skin and reduce the pigmentation in age spots and freckles. Further research has shown other dramatic benefits and today AA-2G is used all over the world-not only for whitening but also for brightening dull looking skin, reversing the effects of aging, and in sunscreen products for protection. |
| Uses | According to the manufacturer, ascorbyl glucoside functions as a time-release version of vitamin C (ascorbic acid), and therefore is more stable than traditional ascorbic acid. It is considered to have skin-lightening and anti-hyperpigmentation properties, thanks to an ability to suppress melanin production. Its skinbrightening capacities are attributed to an apparent ability to reduce pre-existing melanin levels (as in the case of freckles or age spots). Ascorbyl glucoside could also help promote collagen synthesis and help reduce skin inflammation. It is found in antiaging, anti-wrinkle, and sun care products. |
| Uses | 2-O-alpha-D-Glucopyranosyl-L-ascorbic acid reduce the free radicals that result from UV irradiation of the skin, and significantly reduce cell damage and photo-aging. It also promotes collagen synthesis. It can function as an antioxidant. |
| Definition | ChEBI: L-Ascorbic acid-2-glucoside is a glycoside. |
| General Description | Ascorbyl glucoside is a stable form of vitamin C combined with glucose. When properly formulated and absorbed into skin, it breaks down to ascorbic acid (pure vitamin C).2-O-a-D-Glucopyranosyl-L-ascorbic Acid is a useful cosmetic gel and skin cleanser. Once absorbed, its breakdown to vitamin C is gradual, creating what’s known as a reservoir effect within skin. This leads to longer-lasting benefits. |
| Biochem/physiol Actions | 2-O-a-D-glucopyranosyl-L-ascorbic acid or ascorbyl glucoside functions as a skin whitener and radical scavenger in cosmetics. It is responsible for the bleaching action of bleaching cosmetics. This compound is activated in a manner identical to that of vitamin C. The enzyme present in the epidermal basal membrane, ascorbyl phosphatase, slowly converts 2-O-a-D-glucopyranosyl-L-ascorbic acid into vitamin C, thereby maintaining a high vitamin C level in skin throughout the day. |
| Side effects | While pure vitamin C can sting and cause mild irritation, there aren't any side effects we know of with ascorbyl glucoside, says Nussbaum. Still, it is an active ingredient for sure, so you can always test out a small amount elsewhere on your skin to make sure you can tolerate it. |
| Ascorbyl glucoside Preparation Products And Raw materials |
| Introduction | ascorbic acid glucoside is also called VC glucoside, the scientific name O-a-D-glucopyranosyl-L-ascorbic acid (Δacid, abbreviated as AA-2G) is a derivative of VC with a relative molecular mass of 338.27 and a melting point of 158.5-159.5 °c. Due to the poor stability of VC, easy to be oxidized and other shortcomings, it is derived from the alternative product of VC ascorbic acid glucoside, which can replace VC as a acidulant, reducing agent, antioxidant, bleaching agent and stabilizer, widely used in cosmetics, food and medicine and other fields. |
| efficacy and action | 1. Lightening inhibits melanin formation after the conversion of ascorbyl glucoside into Vitamin C into skin cells, the effect of significantly reducing melanin formation is achieved by inhibiting the activity of tyrosinase. Inhibition of tyrosinase results in a decrease in dopaquinone, an intermediate in the synthesis of melanin. Another added benefit is the simultaneous conversion of DOPA quinone to levodopa, which relieves the already formed melanin and, in turn, reduces the pigmentation of the skin. 2. Resistance to UV damage inhibition of UV irradiation on cell damage after ascorbic acid glucoside into vitamin C, can greatly reduce the skin by ultraviolet irradiation of free radicals, significantly reduce skin damage, it plays a role in protecting the skin in sunscreen products. |
| Application | ascorbic acid glucoside is one of the whitening additives approved by the Department of Health, and is recognized as the most stable vitamin C derivative. At the same time, it is also the most commonly used whitening ingredients of major brands. For example, L-Oreal uses C- glycoside derivatives to act synergistically with other components for the prevention or treatment of signs of aging on the skin of the body or face. Ascorbic acid glucoside not only has good whitening effect, but also has stable chemical properties and no irritation to the skin. It is widely used in cosmetics at home and abroad, the following table lists the application of common vitamin C derivatives in cosmetics. |
| whitening principle | the content of the pigment in human skin determines the color of the skin, leucine is the main raw material for the production of the pigment, and tyrosinase is the rate-limiting enzyme in the tyrosine synthesis pathway, which affects the production of melanin mainly by affecting the conversion of tyrosine to DOPA and the oxidation of DOPA to dopaquinone. The whitening mechanism of ascorbyl glucoside is to inhibit the formation of melanin by inhibiting the activity of tyrosinase by using L-keto as a substrate. Its whitening principle can be confirmed by the following picture. |
| preparation | a method for producing ascorbyl glucoside, comprising the following steps: Step 1: The ascorbic acid glucoside reaction solution is separated by nanofiltration to remove the residual VC in the reaction solution to obtain nanofiltration concentrate; Step 2: the nanofiltration concentrate is separated by a continuous fluid separation device to remove glucose from the VC glucoside reaction solution; Step 3: the VC glucoside solution coming out from the continuous fluid separation device is first adjusted by a cation resin and then concentrated by a nanofiltration membrane to remove inorganic salts in the reaction solution to obtain a VC glucoside concentrated solution; Step 4: The concentrated VC glucoside solution is distilled and concentrated under reduced pressure to further increase the concentration of VC glucoside, and then crystallized to obtain VC glucoside. |
Product Packaging：
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage：
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery：
Usually within3-5 working days after full payment.
transport：
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
Packing:
1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);
2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).
3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
P.S.: we accept packaging customization.
Delivery:
1. Stock products are normally shipping within 3 working days.
2. For rush delivery, please contact our sales team for particular arrangement.
Shipping Details:
1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
2. Shipping details & shipping documents will be provided and sent by email.
3. We keep tracking the shippment until clients well received.
4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.
About us
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
FAQ:
1. Are you a trade company or factory
We are a factory with our own trading company.
2.How do you control the quality
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.
3. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
4. Where is your factory located How can I visit the factory
Our factory located in HEBEI, China.
5. Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
6. How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
7. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
8. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
9. How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.