Hebei Nengqian Chemical Import and Export Co., LTD
Assessed Supplier Enterprise Certification
- Assessed
Supplier - 4th
years
Assessed Supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: 86-139-10575315
Tel: +86 15632961819
Tel: +86 18233902561
Tel: +86 15717685612
Tel: +86 16630923639
Tel: +86 18732968538
Tel: +86 18833033983
Tel: +86 19831957301
Mobile: +86 19831957301
Tel: 86-139-10575315
Fax: 4001020630
URL: https://www.nengqianchemical.com/
Province/state: Hebei
City: Handan
Street: Congtai District, La Defense North
MaxCard:
Ms.AnnaCAS NO.28808-62-0
medical grade(1-50)Kilogrammedical grade(50-500)Kilogram
OEM Supply Superior Quality 99% Cytosine CAS 71-30-7
Basic Information:
Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).
Cytosine reagent is used in a wide variety of research applications, as an enzyme-substrate or precursor of effector molecules such as cytosine sugars.
| Product Name: | Cytosine |
| Synonyms: | 4-AMINO-2(1H)-PYRIMIDINONE;4-AMINO-2(1)-PYRIMIDONE;4-AMINO-2-PYRIMIDINOL;4-AMINO-2-OXO-1,2-DIHYDROPYRIMIDINE;4-AMINO-2-HYDROXYPYRIMIDINE;2-Oxy-4-amino pyrimidine;AURORA KA-682;CYTOSINE |
| CAS: | 71-30-7 |
| MF: | C4H5N3O |
| MW: | 111.1 |
| Molecular Formula | C14H16O3 | ||||||||||
| Molar Mass | 232.27 | ||||||||||
| Density | 1.1649 (rough estimate) | ||||||||||
| Melting Point | 114.0 to 118.0 °C | ||||||||||
| Boling Point | 314.44°C (rough estimate) | ||||||||||
| Specific Rotation(α) | (EtOH)-44 | ||||||||||
| Flash Point | 179.3°C | ||||||||||
| Solubility | Easily soluble in chloroform and ethyl acetate. | ||||||||||
| Vapor Presure | 9.29E-06mmHg at 25°C | ||||||||||
| Appearance | Colorless needle crystal | ||||||||||
| Storage Condition | Keep in dark place,Sealed in dry,Store in freezer, under -20°C | ||||||||||
| Refractive Index | 1.5557 (estimate) | ||||||||||
| MDL | MFCD11101451 | ||||||||||
| Physical and Chemical Properties | 化学性质 白色结晶粉末，易溶于氯仿、乙酸乙酯，来源于白鲜皮，白柳(Salix alba L.)的皮。 | ||||||||||
| Use | Uses tryptanthrin is an insecticide that inhibits larval growth and is used for the treatment and protection of crops and agricultural products. Also, it is a natural compound that can be used to treat tumors. | ||||||||||
| In vitro study | Fraxinellone (0-100 μM；12 hours) decreases the percent of PD-L1 positive cells from 20.4% to 11.4% in A549 cells. Cell Viability Assay Cell Line: A549 cells Concentration: 0 μM, 10 μM, 30 μM, 100 μM Incubation Time: 12 hours Result: Inhibited the percent of PD-L1 positive cells. | ||||||||||
| In vivo study | Fraxinellone (oral gavage; 30 and 100 mg/kg; every three days; 30 days) significantly suppresses tumor growth, reduces HIF-1α, pTyr705 STAT3, PD-L1 and VEGF staining compared with the control group in female athymic BALB/c nude mice. Animal Model: BALB/c nude mice Dosage: 30 and 100 mg/kg Administration: Oral gavage; 30 and 100 mg/kg; every three days; 30 days Result: Significantly suppressed tumor growth. | ||||||||||