Keywords

• Tetrahydropyrantriol
• Pro-Xylane,Puri-Xylane
• HYDROXYPROPYL TETRAHYDROPYRANTRIOL

Quick Details

• ProName: pro-xylane 439685-79-7
• CasNo: 439685-79-7
• Appearance: Liquid
• Application: It is a kind of xylose derivative with...
• DeliveryTime: 7-10 working days
• PackAge: In plastic outside weave or according ...
• Port: port of Qingdao、port of Tianjin
• ProductionCapacity: 500 Kilogram/Week
• Purity: >99%
• Storage: Sealed in dry,Room Temperature
• Transportation: We ship goods via DHL, Fedex, UPS, TNT...
• LimitNum: 1 Kilogram
• Grade: Industrial Grade,Food Grade,Pharma Gra...
• Shelf Life: Two years

Superiority

Our Advantage 

Rich Experience 
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. 

Quality service 
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product. 
  
24 hour service 
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage. 

High quality 
Dedicated to serving customers first, we provide reasonable prices, high quality products. 

Introduction

(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is an organic compound commonly abbreviated as TMSA. The following is an introduction to its nature, use, preparation and safety information:

Nature:
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is a colorless liquid with good solubility in water and most organic solvents. Its molecular formula is C9H16O4 and its molecular weight is 188.22g/mol. It has a density of about 0.995 g/mL and a boiling point of about 198-200 ° C.

Use:
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is a commonly used organic synthesis intermediate. It can be used as a substrate, reducing agent and ligand for chiral catalysts. In addition, it can also be used to prepare organic compounds such as drugs, fragrances and dyes.

Method: The preparation of
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER usually involves specific synthetic routes and chemical reactions. A common synthetic method is to obtain (R)-2-methyl-3-methylthiopropionate by oxidation of methyl propyl mercaptan (MPTS), followed by methyl esterification with acetic anhydride to obtain the desired product. Specific synthesis steps and conditions can be adjusted according to needs and experimental conditions.

Safety Information:
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is a chemical, so you need to pay attention to safety when using and handling it. It is combustible and should be kept away from fire and flame. Wear protective gloves, goggles and protective clothing during operation. Avoid contact with skin, eyes and respiratory tract. In case of accidental contact, rinse immediately with water and seek medical assistance. In addition, it should be kept away from children and animals, stored in sealed containers, and placed in a cool, dry place.

Details

Product Description:

Introduction

Use

biological activity

Bose is produced by xylose conversion and has a wide range of biological activities. It can activate the synthesis of mucopolysaccharides (GAGs) and promote the production of hyaluronic acid and collagen; Bose can also improve the adhesion between the dermis and the epidermis. Degree, by inducing the synthesis of structural components of the dermis and epidermis, promote the regeneration of damaged tissues, help maintain the elasticity of the dermis, and. Studies have shown that Bose is easy to biodegrade, does not accumulate in organisms, and has no toxicity.

function

1. Stimulate the generation and construction of GAGs (dry polysaccharide extracellular matrix) (such as gel-like egg autoplasmic network and sugar as scaffolds and intercellular shock absorbers) to make the matrix gel-like, increasing the firmness of cells and skin.

2. As a channel to guide the passage of repair molecules, like some proteins that allow cells to grow.

3. Use the activity of extracellular matrix to send information to young cells and re-stimulate aging cells.

4. Strengthen basement membrane function and reduce allergy and inflammation.

The skin improvement effect of Bose is comprehensive, not only limited to the extracellular matrix, but also the connection between the matrix and cells, the density and firmness of the skin, and the promotion of type VI and Iv collagen egg self-production. Bose, together with nicotinamide and coagulation acid, is listed as Mr. Cai's three favorite multi-effect skin beautifying ingredients.

principle of action

Bose can stimulate the production of mucopolysaccharide GAGs and increase the water content between extracellular matrix. So as to fully fill the ECM gap, make the skin reduce wrinkles, appear more delicate. At the same time, it plays a role in DEJ, promoting the synthesis of collagen VII and collagen IV, making our epidermis and dermis more closely linked, making the whole skin plump, firmer and more elastic.

efficacy

Bose can induce the biosynthesis of GAGs mucopolysaccharide and PG proteoglycan in superficial cortex. The lack of GAGs and PG will lead to the decrease of skin water content and defense ability. Effectively promote the tight connection between epidermis and dermis is better fixed, and the skin is stronger and more flexible. Long-term use can effectively improve wrinkles and fine lines on the face and neck and promote the regeneration of damaged tissues.

Uses and synthesis methods

main efficacy

1. Activate mucopolysaccharides (GAGs) synthesis:

This high-tech ingredient, based on bionics principles, is synthesized by a sugar called xylose that activates mucopolysaccharides (GAGs).

There are a lot of mucopolysaccharides between the extracellular matrix (ECM) of our skin, most of which are carbohydrate polymers (GAG) composed of uronic acid and ammonia sugar, and these mucopolysaccharides play a very important role in the skin, because mucopolysaccharides can absorb moisture and play a role in preventing skin moisture loss.

At the same time, because mucopolysaccharide absorbs a lot of water, it can form a structure that can be imagined as a colloid composed of water. At the same time, the water absorption capacity of the molecular structure of these protein mucopolysaccharides GAGs makes the matrix network structure more elastic, thus helping to improve the firmness of cells and enhance the elasticity of skin. These are important factors that affect the elasticity and texture of skin.

2. Stimulate skin glucosamine (GAGs) production:

Hydroxypropyl tetrahydropyranyl is a glycoprotein mixture that can stimulate the production of skin aminoglycans (GAGs).

GAGs are the main components of the extracellular matrix, and the hyaluronic acid contained in it is one of the main components of GAGs. Hyaluronic acid has strong water absorption and storage capacity, and can be injected into the dermis layer to achieve the effect of filling and tender skin, and the skin is full and elastic. Hyaluronic acid is also commonly used to fill the sunken parts of the skin, including wrinkles.

from the skin structure, GAGS, skin dermis mainly collagen, elastin, extracellular matrix (including GAGs).

synthesis method

The original synthetic route of Bose is: a large amount of xylose (Xylose) extracted from beech is used as the main raw material, and acetylacetone (Acetylacetone) undergoes a Knoevenagel condensation reaction in an alkaline aqueous solution (I. e. active methylene compounds (such as malonate, β-keto, cyanoacetate, nitroacetate, etc.) under the catalysis of ammonia, amine or its carboxylate, it reacts with aldehydes and ketones to undergo aldehyde-alcohol condensation and dehydration to obtain α,β-unsaturated compounds) to generate 1-C-(beta-D-xylopyranosyl)-acetone. After that, it undergoes a reduction reaction with sodium borohydride to reduce the ketone carbonyl group in the product to obtain 1-C-(beta-D-xyranosyl)-2-hydroxy-propane, which is Bose (Pro-xylane).

Use

P> Puri-Xylane, commonly known as Bose, is a xylose derivative with anti-aging activity, which can promote the synthesis of collagen, make skin stronger and more elastic, improve neck fine lines and prevent aging. Bose is a mixture of glycoproteins derived from xylose. Because xylose is abundant in beech trees and has the ability to promote the production of glucosaminoglycans, namely mucopolysaccharides (GAGs). As Bose extracted from beech trees, its effect is similar to xylose.

Bose is also a non-ionic surfactant with good dispersion and emulsification properties. Therefore, the initial low concentration Bose has also been used as an emulsifier or dispersant for skin care products. But after all, there is a skin barrier barrier, and Bose itself has a weak biological activity. Therefore, Bose needs to reach a higher concentration on the skin surface before it can increase the absorption through penetration with the help of concentration gradient. However, the high-concentration Bose has a high viscosity and is not very comfortable to use, so the proportion of Bose in most products is not high.

Our advantage:

1. High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Product Packaging：

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage：

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery：

Usually within3-5 working days after full payment.

transport：

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

Packing:  
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg); 

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg). 

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg). 

P.S.: we accept packaging customization. 

  
Delivery:   

  1. Stock products are normally shipping within 3 working days.  

  2. For rush delivery, please contact our sales team for particular arrangement. 

Shipping Details: 
  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker. 

  2. Shipping details & shipping documents will be provided and sent by email. 

  3. We keep tracking the shippment until clients well received. 

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

About us

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3. How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.