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Hebei Nengqian Chemical Import and Export Co., LTD

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Hebei Nengqian Chemical Import and Export Co., LTD

Country: China (Mainland)

Business Type:Trading Company

Mr.cui

Tel: +86 13910575315

Ms.Anna

Tel: +86 19831957301

Mr.Jacky

Tel: +86 15632927689

Ms.Winnie

Tel: +86 18233902561

Ms.Mandy

Tel: +86 19903295909

Ms.Chris

Tel: +86 16630923639

Ms.Sunny

Tel: +86 18732968538

Mr.Bailey

Tel: +86 15383190639

Mobile: +86 19831957301

Tel: +86 13910575315

Fax: 0310-8698866

URL: http://hbnq1.com/

Province/state: Hebei

City: Handan

Street: Congtai District, La Defense North

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Chrysophanic acid

CAS NO.481-74-3

  • FOB Price: USD: 1,630.00-1,800.00 /Metric Ton Get Latest Price
  • Min.Order: 1 Metric Ton
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    Industrial Grade(1-10)Metric TonIndustrial Grade(10-101)Metric TonIndustrial Grade(100-300)Metric Ton

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Product Details

Keywords

  • 1,8-Dihydroxy-3-methylanthraquinone
  • 3-Methyl-1,8-dihydroxyanthraquinone
  • 9,10-Anthracenedione, 1,8-dihydroxy-3-methyl- (9CI)

Quick Details

  • ProName: Chrysophanic acid 481-74-3
  • CasNo: 481-74-3
  • Molecular Formula: C15H10O4
  • Appearance: White Crystalline Powder
  • Application: chrysophanol has antibacterial, antitu...
  • DeliveryTime: 7-15 working days
  • PackAge: Bag/compartments
  • Port: tianjin
  • ProductionCapacity: 200 Metric Ton/Month
  • Purity: 99%
  • Storage: Dry, away from light, sealed.
  • Transportation: We will choose the mode of transportat...
  • LimitNum: 1 Metric Ton
  • color: White powder

Superiority

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements.

Consistent Quality
Our plant has strict quality control in each manufacturing process. Guaranteed.
Meanwhile all the materials are tested before each shipment in our laboratory to double confirm the quality.

Most competitive pricing
Our company is committed to the production and development of titanium dioxide, we always offer the most competitive pricing to customers to help lower their cost in application.

Shortest delivery time
90% of orders are shipped within 7-10 days after receipt of the prepayment or workable L/C.

Respond in 24 hours to inquiry, feedback or other requirements
Our experienced staff is dedicated to answer all of your inquires, feedback or other requirements in 24 hours.

We welcome you to contact us for more information and look forward to working with yo

Details

Product introduction:

Density 1.2693 (rough estimate)
Melting Point 194-198 °C
Boling Point 357.45°C (rough estimate)
Flash Point 263.9°C
Water Solubility <0.1 g/100 mL at 18 ºC
Solubility Almost insoluble in water, slightly soluble in cold alcohol, easily soluble in boiling ethanol, soluble in benzene, chloroform, ether, glacial acetic acid and acetone, etc., very slightly soluble in petroleum ether.
Vapor Presure 3.31E-10mmHg at 25°C
Appearance golden yellow crystal
Color yellow-orange
Maximum wavelength(λmax) ['429nm(MeOH)(lit.)']
Merck 14,2258
BRN 1252300
pKa 6.63±0.20(Predicted)
Storage Condition Inert atmosphere,Room Temperature
Stability Stable. Incompatible with strong oxidizing agents.
Refractive Index 1.4872 (estimate)
MDL MFCD00001208
Physical and Chemical Properties Melting point 194-198°C
water-soluble <0.1g/100 mL at 18°C
In vitro study Chrysophanic acid (Chrysophanol) is an EGFR/mTOR pathway inhibitor. Chrysophanic acid (Chrysophanol) is a natural anthraquinone compound with anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. Chrysophanic acid (Chrysophanol) preferentially blocked proliferation of SNU-C5 cells, but not of other cell lines (HT7,HT29,KM12C,SW480,HCT116, and SNU-C4) with lower EGFR expression levels. Chrysophanic acid (Chrysophanol) treatment of SNU-C5 cells can inhibit EGF-induced phosphorylation in EGFR and inhibit downstream signaling molecules such as AKT, extracellular signal-regulated kinase (ERK) and activation of mammalian target of rapamycin (mTOR)/ribosomal protein S6 kinase (p70S6K). In BGM(Buffalo green monkey) cells, Chrysophanic acid was also able to inhibit cytopathic effects induced by kidney poliovirus II and type II (small RNA Viridae) and poliovirus.
In vivo study Chrysophanol (CA) improves HFD-induced obesity in C57BL/6 Mice. The in vivo performance of Chrysophanol is performed in male C57BL/6J mice to determine the efficacy of administered Chrysophanol. Mice fed the HFD gained significantly more weight than those fed the standard diet mice. On the other hand, weight gain of Chrysophanol group is significantly less than with the untreated HFD. Mice in the HFD-group gained 23.92 ± 1.74 g of weight, while those in the Chrysophanol group gained 16.72±2 g of weight after 16 weeks.

 

 

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

 

 

 

 

Our advantages: 

1, High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Product Packaging

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery

Usually within3-5 working days after full payment.

transport

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

FAQ: 
1.Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3.How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5.Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6.How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.