Hebei Nengqian Chemical Import and Export Co., LTD
Assessed Supplier Enterprise Certification
- Assessed
Supplier - 4th
years
Assessed Supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: +86 18233902561
Mobile: +86 18233902561
Tel: +86 18233902561
Fax: 4001020630
URL: https://www.nengqianchemical.com/
Province/state: Hebei
City: Handan
Street: Congtai District, La Defense North
MaxCard:
Ms.AnnaCAS NO.50-35-1
medical grade(1-50)Metric Tonmedical grade(50-500)Metric Ton
Our Advantage
Rich Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.
Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.
24 hour service
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.
50-35-1 - Physico-chemical Properties
50-35-1 - Risk and Safety
50-35-1 - StandardAuthoritative Data Verified Data This product is (±)-N-(2, 6-dioxo-3-piperidinyl)-phthalimide. The content of C13H10N204 shall be 98.0% ~ 102.0% calculated as dry product.
50-35-1 - TraitAuthoritative Data Verified Data
50-35-1 - Differential diagnosisAuthoritative Data Verified Data
50-35-1 - ExamAuthoritative Data Verified Data Related substances take about 0.lg of this product, weigh it accurately, put it in a 50ml measuring flask, add an appropriate amount of acetonitrile-water-phosphoric acid (50:50:0.1), ultrasonic to dissolve and dilute to the scale, shake well, take 10ml accurately, put it in a 100ml measuring flask, add 10ml of phosphoric acid solution (1-100), dilute it to scale with water, shake well, and use it as a test solution, add acetonitrile to dissolve and dilute to prepare a solution containing 1 mg per 1 ml as solution (1); Take an appropriate amount of phthalic acid reference substance, weigh it accurately, and use acetonitrile-water (80:5). Dissolve and quantitatively dilute to make a solution containing 1 mg per 1 ml, take an appropriate amount with precision, and quantitatively dilute with acetonitrile to make a solution containing 0 mg per 1 ml. 1 mg of the solution, as solution (2); Precision measure the solution (1), (2) each 2ml, put the same 100ml measuring flask, with acetonitrile-water-phosphoric acid (50:50:0.1) dilute to the scale, shake well, take 10ml accurately, put it in a 100ml measuring flask, add 10ml of phosphoric acid solution (1-100), dilute to the scale with water, shake well, as a control solution. According to the test of high performance liquid chromatography (General rule 0512), silica gel bonded with eighteen alkyl silane was used as the filler (×, 4um or equivalent column); Acetonitrile-water-phosphoric acid (5:95:0.1) as mobile phase A, acetonitrile-water-phosphoric acid (15:85:0.1) as mobile phase B; Flow rate was 2ml per minute; Gradient elution was carried out according to the following table; Detection wavelength was 218nm. Take the reference solution 200 u1, inject human liquid chromatograph, adjust the flow rate, so that the retention time of thalidomide peak is about 14 minutes; The relative retention time of phthalic acid peak and thalidomide peak is about 0.3. Take 200 u1 of the test solution and the reference solution respectively, inject the human liquid chromatograph and record the chromatogram. In the chromatogram of the test solution, if there are impurity peaks, the area of the phthalic acid peak shall be calculated according to the external standard method, and the single impurity shall not exceed 0.1%, and the total amount of the impurity shall not exceed 0.3%. residual solvent take 0.lg of this product, precision weighing, put it in 10ml measuring flask, add dimethyl sulfoxide to dissolve and dilute to the scale, shake, as a test solution; Take an appropriate amount of N,N-dimethylformamide, precision weighing, quantitative dilution with dimethyl sulfoxide to make a solution containing 8.8ug per 1 ml, shake, as a reference solution. According to the test of residual solvent determination (General 0861 third method), polyethylene glycol (PEG-20M) is used as stationary liquid; The initial temperature is 50°C, the temperature is maintained for 3 minutes, and the temperature is raised to 200°C at a rate of 20°C per minute, it was maintained for 7 minutes; The inlet temperature was 250°C; The detector temperature was 280°C. The sample solution and the reference solution were respectively 1 u1 and injected into the gas chromatograph. According to the external standard method to calculate the peak area, N,N-dimethylformamide residues should comply with the provisions. loss on drying take this product and dry it at 105°C for 4 hours, and the weight loss shall not exceed 0.5% (General rule 0831). ignition residue take l.Og of this product and check it according to law (General rule 0841). The residue left shall not exceed 0.3%. Heavy metals The residue left under the item of ignition residue shall not contain more than 20 parts per million of heavy metal when examined by law (General rule 0821).
50-35-1 - Content determinationAuthoritative Data Verified Data measured by high performance liquid chromatography (General 0512). chromatographic conditions and system suitability test silica gel bonded with eighteen alkyl silane was used as the filler; Acetonitrile-water-phosphoric acid (15:85:0.1) was used as the mobile phase; The detection wavelength was 237nm. The number of theoretical plates shall not be less than 7000 based on the thalidomide peak. assay take about 0.1kg of this product, weigh it accurately, put it in a 100ml measuring flask, add 80ml of acetonitrile, dissolve it by ultrasound, let it cool, dilute it to the scale with acetonitrile, shake it well, take 10ml accurately, put it in a 100ml measuring flask, add 10ml of phosphoric acid solution (1-100), dilute with water to the scale, and shake well. 20 u1 was accurately measured, and human liquid chromatography was injected, and the chromatogram was recorded. Another thalidomide reference substance was taken, and the same method was used for determination. According to the external standard method to calculate the peak area, that is.
50-35-1 - CategoryAuthoritative Data Verified Data immunomodulatory drugs.
50-35-1 - StorageAuthoritative Data Verified Data sealed storage.
50-35-1 - Thalidomide tabletsAuthoritative Data Verified Data This product contains thalidomide (C13H10N204) should be 93.0% to 107.0% of the label. trait This product is white or off-white. identification
examination
Content determination Take 20 tablets of this product, precision weighing, fine grinding, precision weighing appropriate amount (about equivalent to thalidomide O.lg ), put it in a 100ml measuring flask, add 80ml of acetonitrile, sonicate thalidomide to dissolve, let it cool, dilute with acetonitrile to the scale, shake well, filter, take 10ml of continued filtrate with precision, put it in a 100ml measuring flask, Add 10ml of phosphoric acid solution (1-100), dilute it to the scale with water, shake it well, and use it as a test solution, and measure it according to the method under the thalidomide content determination item. category Same as thalidomide. specification (l)25mg (2)50mg storage light shielding, sealed storage. |
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
Superiority
As a reliable partner for Chinese market, we are specialized in chemical raw materials; consolidate sourcing, marketing, sales, distribution and after-sale services, providing our partners with sourcing evaluation, technology supports, toll/contract manufacture, investment solution and suitable partnership establishment in China.
Service we can provide:
1. provide costomers with "one-stop"packaging service,from manufacture ,research,development,production,export and so on
2. Quality control, before shipment.
3. Prompt shipment with professional documents
4. Packing as your request, with photo before shipment
5.Mix and different products in ONE PCL,increase the working efficiency for customers.
6.We can export from many China main ports,convenient for the customes provide logistics services.
Our advantages:
1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
Product Packaging：
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage：
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery：
Usually within3-5 working days after full payment.
transport：
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
FAQ:
1.Are you a trade company or factory
We are a factory with our own trading company.
2.How do you control the quality
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.
3.How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
4. Where is your factory located How can I visit the factory
Our factory located in HEBEI, China.
5.Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
6.How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
7. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
8. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
9.How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.