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Ms.AnnaCAS NO.630-94-4
medical grade(1-50)Kilogrammedical grade(50-500)Kilogram
OEM Supply Superior Quality 99% Cytosine CAS 71-30-7
Basic Information:
Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).
Cytosine reagent is used in a wide variety of research applications, as an enzyme-substrate or precursor of effector molecules such as cytosine sugars.
| Product Name: | Cytosine |
| Synonyms: | 4-AMINO-2(1H)-PYRIMIDINONE;4-AMINO-2(1)-PYRIMIDONE;4-AMINO-2-PYRIMIDINOL;4-AMINO-2-OXO-1,2-DIHYDROPYRIMIDINE;4-AMINO-2-HYDROXYPYRIMIDINE;2-Oxy-4-amino pyrimidine;AURORA KA-682;CYTOSINE |
| CAS: | 71-30-7 |
| MF: | C4H5N3O |
| MW: | 111.1 |
| Molecular Formula | C22H26N2O4 |
| Molar Mass | 382.46 |
| Density | 1.25 |
| Melting Point | 210°C |
| Boling Point | 562.7±50.0 °C(Predicted) |
| Specific Rotation(α) | (CHCl3)-21；(c, 1 in Py)+23 |
| Flash Point | 294.1°C |
| Solubility | Soluble in chloroform, soluble in acetone, ethanol, benzene, slightly soluble in ether and ethyl acetate, insoluble in petroleum ether. |
| Vapor Presure | 1.09E-12mmHg at 25°C |
| Appearance | Light yellow powder |
| pKa | 13.54±0.60(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.605 |
| MDL | MFCD20527288 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Uncaria. |
| In vitro study | Isocorynoxeine inhibits 5-HT 2A receptor-mediated 5-HT currents. Isocorynoxeine prefer to interact with 5-HT 2A receptors rather than with 5-HT 2C receptors in the brain.Isocorynoxeine exhibits less potent inhibitory activity (with IC 50 values of > 100 μM) against the 5-HT 2C receptor-mediated response than the 5-HT 2A receptor-mediated response in oocytes. Isocorynoxeine dose-dependently and competitively inhibits 5-HT-evoked currents in Xenopus oocytes expressing 5-HT 2A receptors, but has less of a suppressive effect on those in oocytes expressing 5-HT 2C receptors. |
| In vivo study | The effects of Rhynchophylline, Corynoxeine, and Isocorynoxeine, isorhynchophylline-related alkaloids present are tested in Uncaria species, on 5-MeO-DMT-induced head-twitch behaviour in reserpinized mice. Neither Rhynchophylline [H=1.369, P=0.504] nor Corynoxeine [H=0.242, P=0.886] affects the behaviour, while Isocorynoxeine significantly attenuates it at 30 mg/kg (i.p.) [H=7.582, P<0.01]. |