Hebei Nengqian Chemical Import and Export Co., LTD
Assessed Supplier Enterprise Certification
- Assessed
Supplier - 4th
years
Assessed Supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: +86 13910575315
Tel: +86 19831957301
Tel: +86 15632927689
Tel: +86 18233902561
Tel: +86 19903295909
Tel: +86 16630923639
Tel: +86 18732968538
Tel: +86 15383190639
Mobile: +86 19831957301
Tel: +86 13910575315
Fax: 0310-8698866
URL: http://hbnq1.com/
Province/state: Hebei
City: Handan
Street: Congtai District, La Defense North
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CAS NO.79725-98-7
Industrial Grade(1-10)Metric TonIndustrial Grade(10-101)Metric TonIndustrial Grade(100-300)Metric Ton
With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements.
Consistent Quality
Our plant has strict quality control in each manufacturing process. Guaranteed.
Meanwhile all the materials are tested before each shipment in our laboratory to double confirm the quality.
Most competitive pricing
Our company is committed to the production and development of titanium dioxide, we always offer the most competitive pricing to customers to help lower their cost in application.
Shortest delivery time
90% of orders are shipped within 7-10 days after receipt of the prepayment or workable L/C.
Respond in 24 hours to inquiry, feedback or other requirements
Our experienced staff is dedicated to answer all of your inquires, feedback or other requirements in 24 hours.
We welcome you to contact us for more information and look forward to working with yo
Product introduction:
| Description | Kojic acid is a widely used skin lighten-ing agent as it inhibits catecholase activity of tyrosinase. Derivatives of kojic acid such as kojic acid dipalmitate are easilyabsorbed through skin and are more effective than kojic acid. kojic acid dipalmitate is an effective tyrosinase inhibitor that stunts melanin production, making it a powerful skin whitening agent. It can balance skin tones, fade dark spots, and eliminate free radicals. kojic acid dipalmitate is a topical cream formulation indicated for the treatment of post-inflammatory hyperpigmentation, melasma and hyper-melanotic skin pigmentation disorders. Kojic Acid Dipalmitate can lighten the skin pigmentation and corrects discoloration in adults. |
| Chemical Properties | Kojic acid dipalmitate is a White to pale yellow powder, Soluble in oil, alcohol, mineral oil and esters (ethyl acetate). It is light and heat stable, while kojic acid tends to oxidize over time. Kojic acid dipalmitate is stable within a wide pH range of 4-9, It is more easily absorbed into skin when it is incorporated into a cream as compared with kojic acid. |
| Uses | kojic acid dipalmitate is classified as an emollient, preparations containing kojic acid dipalmitate are said to inhibit uV-induced erythema. |
| Application | kojic acid dipalmitate is a diesterified derivative of tretinoin. It is considered superior to tretinoin in its whitening ability and is more stable than tretinoin in cosmetic formulations. It is commonly used in sunscreens and after-sun products, colour cosmetics, whitening products, anti-ageing products, creams and lotions. |
| benefits | Kojic acid dipalmitate has the advantage that it does not complex with metal ions, does not change colour, is light and heat stable and is compatible with most cosmetic ingredients. Therefore, in addition to whitening the skin, it has anti-aging properties, treats melasma, reduces scars, and has antibacterial (antifungal) benefits. |
| Mechanism of action | Kojic acid dipalmitate is able to inhibit skin pigmentation by inhibiting tyrosinase activity. Its ability to inhibit melanin formation makes it effective in whitening darker skin or darker skin areas. Its effect is enhanced when combined with glucosamine derivatives such as N-acetylglucosamine (NAG). |
| Synthesis | (1) Synthesis of palmitoyl chloride: Add a certain amount of palmitic acid to a three-necked flask, dissolve it with CCl, and slowly drip PClR into the three-necked flask with a dropping funnel, stirring at a low speed to react. Maintain the temperature for the reaction, then increase the temperature for the reaction, stop the reaction and separate and remove H.PO.(2) Synthesis of kojic acid dipalmitate: Add a certain amount of kojic acid to a three-necked flask, dissolve it with acetone/pyridine solution, and then slowly drip palmitoyl chloride into the three-necked flask with a dropping funnel to react. After the reaction, wash the product first, filter it on a Buchner funnel, and repeat the washing at least 3 times. Take out the product, recrystallize it with a solvent, and vacuum dry it to obtain white, flaky crystals. |
| References | [1] Nishma Tanveer PhD, Naveed Akhtar PhD, Haji Muhammad Shoaib Khan PhD. “Whitening effect of kojic acid dipalmitate loaded nanosized ethosomal gel for the treatment of hyperpigmentation: In vitro and in vivo characterization.” Journal of Cosmetic Dermatology 21 12 (2022): 6850–6862. |
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
Our advantages:
1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
Product Packaging：
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage：
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery：
Usually within3-5 working days after full payment.
transport：
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
FAQ:
1.Are you a trade company or factory
We are a factory with our own trading company.
2.How do you control the quality
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.
3.How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
4. Where is your factory located How can I visit the factory
Our factory located in HEBEI, China.
5.Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
6.How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
7. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
8. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
9. How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.