Hebei Nengqian Chemical Import and Export Co., LTD
Assessed Supplier Enterprise Certification
- Assessed
Supplier - 4th
years
Assessed Supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: +86 18233902561
Mobile: +86 18233902561
Tel: +86 18233902561
Fax: 4001020630
URL: https://www.nengqianchemical.com/
Province/state: Hebei
City: Handan
Street: No.1722, Block C, Yangguang Xinzhuo Plaza, 256 Renmin West Road, Fuxing District, Handan City, Hebei Province
MaxCard:
Ms.AnnaCAS NO.79794-75-5
Pharmaceutical grade(1-5)GramPharmaceutical grade(6-99)Gram
Our advantages:
1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
Product Packaging：
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage：
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery：
Usually within3-5 working days after full payment.
transport：
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
| Molecular Formula | C22H23ClN2O2 |
| Molar Mass | 382.88 |
| Density | 1.261±0.06 g/cm3(Predicted) |
| Melting Point | 134-136°C |
| Boling Point | 531.3±50.0 °C(Predicted) |
| Water Solubility | It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol. |
| Solubility | DMSO: 26mg/mL, soluble |
| Appearance | powder |
| Color | white |
| Merck | 14,5578 |
| pKa | 4.27±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents. |
| MDL | MFCD00672869 |
| Physical and Chemical Properties | Crystallization from acetonitrile, melting point 134-136 °c. |
| Use | New national Class II anti-allergic drug for the relief of nasal and non-nasal symptoms of seasonal allergic rhinitis and the relief of chronic urticaria |
| In vitro study | Loratadine was identified as a selective inhibitor of B(0)AT 2, with an IC 50 of 4 μm, with low or no activity against several other members of the SLC6 family. In Der p 1 and or anti-Fc small RI pre-cultured human Fc small RI cells, Loratadine concentration-dependent inhibition of histamine and leukotriene C4 release. Loratadine(0.1 mM) also inhibited the release of histamine, leukotriene C4, and PGD2 in purified HLMC activated by a small amount of RI against FCR. Loratadine concentration-dependently inhibited the release of histamine, tryptase, LTC4, and PGD 2 in purified HSMC stimulated against a small amount of RI. In Human Umbilical vein endothelial cells, Loratadine significantly inhibited histamine-induced IL-6 and IL-8 secretion. In human Ltk-cells transfected with the hKv1.5 channel gene, Loratadineh blocked the Kv1.5 channel in a concentration-, voltage-, time-and use-dependent manner at concentrations above therapeutic plasma levels. Loratadineh inhibited rhinovirus-induced upregulation of ICAM-1 in the main bronchus or transformed (A549) respiratory epithelial cells. Loratadineh also inhibited rhinovirus infection-induced ICAM-1 mRNA in a dose-dependent manner, and they completely inhibited rhinovirus-induced activation of the ICAM-1 promoter. |
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
FAQ:
1. Are you a trade company or factory
We are a factory with our own trading company.
5. Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
6. How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
7. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
8. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
9. How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.