Hebei Nengqian Chemical Import and Export Co., LTD
Assessed Supplier Enterprise Certification
- Assessed
Supplier - 4th
years
Assessed Supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: 86-139-10575315
Tel: +86 15632961819
Tel: +86 18233902561
Tel: +86 15717685612
Tel: +86 16630923639
Tel: +86 18732968538
Tel: +86 18833033983
Tel: +86 19831957301
Mobile: +86 19831957301
Tel: 86-139-10575315
Fax: 4001020630
URL: https://www.nengqianchemical.com/
Province/state: Hebei
City: Handan
Street: Congtai District, La Defense North
MaxCard:
Ms.AnnaCAS NO.126-19-2
Industrial Grade(1-10)Metric TonIndustrial Grade(10-101)Metric TonIndustrial Grade(100-300)Metric Ton
With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements.
Consistent Quality
Our plant has strict quality control in each manufacturing process. Guaranteed.
Meanwhile all the materials are tested before each shipment in our laboratory to double confirm the quality.
Most competitive pricing
Our company is committed to the production and development of titanium dioxide, we always offer the most competitive pricing to customers to help lower their cost in application.
Shortest delivery time
90% of orders are shipped within 7-10 days after receipt of the prepayment or workable L/C.
Respond in 24 hours to inquiry, feedback or other requirements
Our experienced staff is dedicated to answer all of your inquires, feedback or other requirements in 24 hours.
We welcome you to contact us for more information and look forward to working with yo
Product introduction:
| Density | 1.0362 (rough estimate) |
| Melting Point | 194°C |
| Boling Point | 474.91°C (rough estimate) |
| Specific Rotation(α) | D25 -75°; 25546 -89° (c = 0.5 in CHCl3) |
| Flash Point | 266.2°C |
| Solubility | Ethanol : 1 mg/mL (2.40 mM; Need ultrasonic) |
| Vapor Presure | 7.83E-13mmHg at 25°C |
| Appearance | Colorless long needle crystal |
| Merck | 13,8456 |
| pKa | 15.14±0.70(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4700 (estimate) |
| MDL | MFCD00270414 |
| Physical and Chemical Properties | Brown to dark brown tea liquid, with special odor. It has good foaming performance, low proportion, stable foam, and the pH value of 2~10 can be used. The main component of Sapona saponin (Sarsa-sapoge-nin), melting point of 194~195 ℃, some of the mold, yeast antibacterial. |
| In vitro study | The treatment of Sarsasapogenin can increase the number of S-phase Hela cells, resulting in the accumulation of G2/M phase cells. It can induce apoptosis of HeLa cells by inducing the mitochondrial apoptosis pathway dependent on caspase. Sarsasapogenin induces the activation of endoplasmic reticulum stress response signaling pathway, and induces toxicity to human cervical cancer cells through cell cycle arrest, ROS-mediated mitochondrial pathway and endoplasmic reticulum stress response pathway. Sarsasapogenin also induces early activation of UPR, activating CHOP, which may promote lineal membrane permeabilization by dephosphorylating Akt, thus transmitting apoptotic signals from the endoplasmic reticulum to mitochondria. Sarsasapogenin effectively inhibited the activation of NF-κB and MAPK, and inhibited the phosphorylation of IRAK1, TAK1, and IκBα in macrophages stimulated by LPS. Sarsasapogenin also inhibits the binding of LPS to TLR4 receptors in macrophages and inhibits the polarization of M2 to M1 macrophages. |
| In vivo study | Oral administration of sarsasapogenin in mice can inhibit the colon shortening and myeloperoxidase activity induced by TNBS, reduce the activation of NF-κB and the levels of IL-1β, TNF-α, IL-6, and enhance the expression level of IL-10. In colonic lamina propria, sarsasapogenin inhibited Th17 cell differentiation and induced Treg cell differentiation. In Vivo, Sarsasapogenin effectively inhibits the inflammatory response. |
| biological activity | Sarsasapogenin (SAR, Parigenin) is a steroidal saponin, which can induce ROS production and activate unfolded protein response (UPR) signaling pathway. SAR can effectively inhibit the activation of NF-κB and MAPK, and inhibit the phosphorylation of IRAK1, TAK1 and IκBα in macrophages stimulated by LPS. |
| Target | Value |
| use | emulsifier; Foaming agent; Preservative. Mainly used for refreshing drinks, foaming sweets, mixed wines, etc. GB 2760-2000 specifies spices for food that are allowed to be used. |
| Production method | The whole plant of Yucca arborescens and Yucca schidirera, which are produced in the deserts of Mexico and Central and South America, is extracted with hot water or mild-temperature aqueous ethanol or aqueous isopropyl alcohol after cutting. |
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
Our advantages:
1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
Product Packaging：
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage：
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery：
Usually within3-5 working days after full payment.
transport：
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
FAQ:
1.Are you a trade company or factory
We are a factory with our own trading company.
2.How do you control the quality
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.
3.How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
4. Where is your factory located How can I visit the factory
Our factory located in HEBEI, China.
5.Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
6.How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
7. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
8. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
9. How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.