Hebei Nengqian Chemical Import and Export Co., LTD
Assessed Supplier Enterprise Certification
- Assessed
Supplier - 4th
years
Assessed Supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: 86-139-10575315
Tel: +86 15632961819
Tel: +86 18233902561
Tel: +86 15717685612
Tel: +86 16630923639
Tel: +86 18732968538
Tel: +86 18833033983
Tel: +86 19831957301
Mobile: +86 19831957301
Tel: 86-139-10575315
Fax: 4001020630
URL: https://www.nengqianchemical.com/
Province/state: Hebei
City: Handan
Street: Congtai District, La Defense North
MaxCard:
Ms.AnnaCAS NO.140-18-1
Pharmaceutical grade(1-50)KilogramPharmaceutical grade(51-99)Kilogram
Our Advantage
Rich Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.
Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.
24 hour service
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is an organic compound commonly abbreviated as TMSA. The following is an introduction to its nature, use, preparation and safety information:
Nature:
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is a colorless liquid with good solubility in water and most organic solvents. Its molecular formula is C9H16O4 and its molecular weight is 188.22g/mol. It has a density of about 0.995 g/mL and a boiling point of about 198-200 ° C.
Use:
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is a commonly used organic synthesis intermediate. It can be used as a substrate, reducing agent and ligand for chiral catalysts. In addition, it can also be used to prepare organic compounds such as drugs, fragrances and dyes.
Method: The preparation of
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER usually involves specific synthetic routes and chemical reactions. A common synthetic method is to obtain (R)-2-methyl-3-methylthiopropionate by oxidation of methyl propyl mercaptan (MPTS), followed by methyl esterification with acetic anhydride to obtain the desired product. Specific synthesis steps and conditions can be adjusted according to needs and experimental conditions.
Safety Information:
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is a chemical, so you need to pay attention to safety when using and handling it. It is combustible and should be kept away from fire and flame. Wear protective gloves, goggles and protective clothing during operation. Avoid contact with skin, eyes and respiratory tract. In case of accidental contact, rinse immediately with water and seek medical assistance. In addition, it should be kept away from children and animals, stored in sealed containers, and placed in a cool, dry place.
| overview | cinnamic acid is also called cinnamic acid and cinnamic acid. Molecular structure: C6H5CHCHCOOH, English Trans2Cinnamicacid, white monoclinic crystal in appearance, slightly cinnamon smell. Cinnamic acid is an important intermediate in fine chemical synthesis, which is widely used in chemical products such as medicine, perfume, plastic and photosensitive resin. There are two isomers, cis and trans, usually in trans. Slightly soluble in water, easily soluble in acid, benzene, acetone, glacial acetic acid, soluble in ethanol, methanol and chloroform. When cinnamic acid is heated, styrene is decarboxylated, and benzoic acid is formed when oxidized. Cinnamic acid exists in Toru balsam, Suhe balsam, etc. Cinnamic acid is mainly used to make esters, for the preparation of lilac type and other floral essence and medicine. |
| uses and functions of cinnamic acid (in essence and spice) | 1. prepare apples, cherries, and can be used as apple essence, cherry essence, fruit essence and flower essence. 2. It can be used as an aromatic mixture in soap, shampoo, washing powder and daily cosmetics. 3. It has the effect of inhibiting the formation of black tyrosinase, has a certain isolation effect on ultraviolet rays, and can make brown spots lighter or even disappear. It is one of the indispensable ingredients in advanced sunscreen. 4. Cinnamic acid itself is a kind of spice, which has a good fragrance preservation effect. It is usually used as a raw material to make the aroma of the main spice more fragrant and volatile. Various esters of cinnamic acid (such as A, B, C, D, etc.) can be used as a fixer for beverages, cold drinks, candy, alcohol and other foods. |
| in food additives | 1. cinnamic acid uses microbial enzymatic synthesis of L-phenylalanine. L-phenylalanine is the main raw material of sweet aspartame (Aspartame), an important food additive. 2. Unilever of the United Kingdom has obtained the World Intellectual Property Organization patent PCTInt. Appl. Wo01 87,080(2001,11.22) This article introduces the composition of cinnamic acid and pasteurization additives, which have strong sterilization and antiseptic effects. 3. Cinnamic acid is also a component of capsaicin synthase-cinnamic acid hydrolase, which can be used to cultivate excellent varieties of capsaicin with high-yield capsaicin content, which will greatly improve the quality of capsicum and effectively promote the industrialization of capsicum. 4. The use of cinnamic acid to prevent mildew, preservative and sterilization can be applied to the preservation and preservation of grains, vegetables and fruits. 5. It can also be used in wine to make it bright in color. 6. Cinnamic acid has a strong excitatory effect and can be widely and directly added to all foods. |
| in the pharmaceutical industry | in the pharmaceutical industry, lactic acid, an important drug for the treatment of coronary heart disease, can be synthesized. It can also synthesize chlorphenambutyric acid and cinnamon phenoperazine, which are used as spinal cone bone relaxants and antispasmodics. Mainly used for cerebral thrombosis, cerebral arteriosclerosis, coronary arteriosclerosis and other diseases. It has obvious inhibitory effect on the proliferation of lung adenocarcinoma cells. Cinnamic acid is an effective inhibitor for the A- 5491 of human lung adenocarcinoma cells and has great application value in anti-cancer. |
| in beauty | cinnamic acid can be used in beauty. casinase is the key enzyme for melanin synthesis. it initiates the level chain reaction from tyrosine to melanin biopolymer. cinnamic acid has the effect of inhibiting the formation of black tyrosinase, has a certain isolation effect on ultraviolet rays, and can make brown spots lighter or even disappear, it is one of the essential ingredients in advanced sunscreen. The significant antioxidant effect of cinnamic acid has a good effect on slowing down the appearance of wrinkles. |
| In the pesticide industry | In the agricultural industry, cinnamic acid is used as a growth promoter and long-acting fungicide for fruit and vegetable preservation. |
| in organic synthesis and chemical engineering | in organic chemical synthesis, cinnamic acid can be used as a slow-release agent for galvanized sheet, a heat stabilizer for polyvinyl chloride, a crosslinking agent for polycarbamate, a flame retardant for hydanyl and polycaprolactam, and a chemical analysis reagent. It is also a reagent for determining the separation of uranium and vanadium; it is also the most important synthetic raw material for negative photosensitive resins. The main synthesis of cinnamic acid ester, polyvinyl cinnamic acid ester, polyethylene oxycinnamic acid ethyl ester and the side group for the epoxy resin of cinnamic acid ester. Used in plastics, it can be used as a heat stabilizer for PVC, sterilization, anti-mold and deodorant, and can also be added in rubber and foam plastics to make anti-odor shoes and insoles, and can also be used in cotton cloth and various synthetic fibers, leather, Paint, shoe polish, straw mat and other products to prevent mildew. |
| Uses | Cinnamic acid, also known as phenylacrylic acid, is an intermediate of rodenticide bromadiolone. Cinnamic acid is used to prepare L-phenylalanine, as an intermediate for coronary heart disease medicine Xinkean, and can also be used to make local anesthetics, fungicides, hemostatic drugs, etc.; it is used in the perfume industry to prepare phenyl methyl acrylate, ethyl ester and phenyl ester, used as food and cosmetic spices, and has a better fragrance-preserving effect; used for pesticide industry growth promoters, long-acting fungicides, preservatives for fruits and vegetables, etc.; also used in the production of photosensitive resins The main raw material vinyl cinnamic acid. Cinnamic acid is a reagent for the determination of uranium, vanadium and the separation of thorium. It is often used as a cream or a fixative, especially suitable for oriental fragrance. Among the edible flavors, it is mostly used for spices such as cinnamon, and occasionally used in cherries and honey flavors. Cinnamic acid can be used to synthesize chloramphenicol cinnamate, cardiostat, etc., and can also be used to prepare anesthetics, fungicides and hemostatic drugs. In the perfume industry, it can be widely used to synthesize methyl cinnamate, ethyl cinnamate and phenyl cinnamate. Determination of uranium and vanadium, separation of thorium, and production of cinnamic acid esters. Standard for the determination of double bonds by organic microanalysis. |
| production method | is obtained by condensation of benzaldehyde and acetic anhydride. Benzaldehyde, acetic anhydride and sodium acetate are put into a dry glass-lined reaction pot, stirred and heated, and refluxed for 7-9h. Acetic acid is recovered at normal pressure to 140 ℃, and acetic anhydride is recovered at reduced pressure until the material is viscous. Dissolve with heated water, and recover unreacted benzaldehyde by steam distillation until no oil is evaporated. Add water and liquid alkali to dissolve, add activated carbon, and reflux at 100 ℃ for 15min. Filter while hot. The filtrate is neutralized with hydrochloric acid to pH = 1, cooled to 10 ℃, crystallized, filtered and dried to obtain cinnamic acid. 58% yield. the preparation method is to add benzaldehyde, acetic anhydride and anhydrous sodium acetate in the reactor, heat at 180 ℃ for 8 h, then cool to 80~100 ℃, pour into water, carry out steam distillation, remove unreacted benzaldehyde, add appropriate amount of hydrochloric acid to acidify the solution after distillation, and precipitate the product. |
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
Product Packaging：
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage：
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery：
Usually within3-5 working days after full payment.
transport：
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
Packing:
1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);
2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).
3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
P.S.: we accept packaging customization.
Delivery:
1. Stock products are normally shipping within 3 working days.
2. For rush delivery, please contact our sales team for particular arrangement.
Shipping Details:
1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
2. Shipping details & shipping documents will be provided and sent by email.
3. We keep tracking the shippment until clients well received.
4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.
About us
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
FAQ:
1. Are you a trade company or factory
We are a factory with our own trading company.
2.How do you control the quality
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.
3. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
4. Where is your factory located How can I visit the factory
Our factory located in HEBEI, China.
5. Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
6. How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
7. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
8. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
9. How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.