Hebei Nengqian Chemical Import and Export Co., LTD
Assessed Supplier Enterprise Certification
- Assessed
Supplier - 4th
years
Assessed Supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: +86 18732968538
Mobile: +86 18732968538
Tel: +86 18732968538
Fax: 4001020630
URL: https://www.nengqianchemical.com/
Province/state: Hebei
City: Handan
Street: Congtai District, La Defense North
MaxCard:
Ms.AnnaCAS NO.141-01-5
Pharmaceutical grade(1-50)KilogramPharmaceutical grade(51-99)Kilogram
Our Advantage
Rich Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.
Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.
24 hour service
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
| Molar Mass | 169.9 |
| Density | 2.435 |
| Melting Point | >280°C |
| Water Solubility | Soluble in water (0.14 g/100 ml at 25°C). |
| Solubility | Slightly soluble in water, very slightly soluble in ethanol (96 per cent). |
| Vapor Presure | 0Pa at 25℃ |
| Appearance | solid |
| Color | Dark Red to Dark Brown |
| Exposure Limit | ACGIH: TWA 1 mg/m3NIOSH: TWA 1 mg/m3 |
| Merck | 14,4046 |
| Storage Condition | Refrigerator |
| Stability | Stability |
| MDL | MFCD00058315 |
| Physical and Chemical Properties | Density 2.435 melting point> 280°C |
| Use | Anti-anemia drugs for the treatment of iron deficiency anemia, but also a large number of food and feed additives |
| organic iron supplement | iron is one of the essential trace elements in animal body. It is a component of heme, myoglobin, cytochrome, etc., and is closely related to the processes of hematopoiesis, oxygen carrying, and production capacity of animals. When animals synthesize somatic proteins, they need the effect of nylin, and iron is an essential substance for the synthesis of nylin. When animals lack iron, the first manifestations are growth retardation, weak disease resistance, reduced feed utilization, and poor reproductive ability, followed by anemia, diarrhea, and death. Ferrous fumarate, also known as ferric fumarate, is a safe and efficient organic nutritional iron supplement. It belongs to organic iron (including: iron lysine, iron glycinate, iron methionine, etc.), Its organic divalent iron content is as high as 30% or more. After ferrous fumarate is absorbed, the divalent iron ions are easier to decompose. It does not require additional energy to enter red blood cells, does not stimulate the intestines and stomach, and can improve and maintain the normal level of heme, it can be used as a nutritional additive for a long time and clinically used to treat iron deficiency anemia. Ferrous fumarate is absorbed in the duodenum and upper jejunum in the form of ferrous ions in animals. Most of the absorbed iron is involved in the synthesis of hemoglobin in the bone marrow, and the remaining part is stored in the reticuloendothelial cells of the bone marrow, liver and spleen in the form of ferritin and hemosiderin, and a part exists in the intestinal mucosal cells. This absorption method is different from inorganic iron supplements (ferrous sulfate, ferrous carbonate, iron oxide, etc.). It can alleviate the competitive antagonism between trace elements during absorption, does not destroy vitamins, and does not catalyze oxidation The reaction has good compatibility with various nutrients and can smoothly pass the body's absorption barrier, which not only greatly improves the absorption and utilization of iron, but also increases the absorption rate of other elements. The main route of iron excretion is intestinal and skin, urine and sweat glands also have a small amount of excretion. Most iron can be reused when hemoglobin molecules are released after being destroyed. |
| identification test | take about 1.5g of sample, add 25ml of 1:1 dilute hydrochloric acid, dilute to 50ml with water, heat to completely dissolve, cool, filter with a fine-hole sintered glass crucible, wash the precipitate with 3% dilute hydrochloric acid, save the filtrate for identification test 2, and dry the filter residue at 105 ℃. Add 3m1 water and 7 mL1mol/L sodium hydroxide to 400mg of dry filter residue and stir until completely dissolved. Dilute hydrochloric acid test solution (TS-117) is added dropwise until the solution is just acidic to litmus paper, and 1g of p-nitrobenzyl bromide and 10ml of ethanol are added to heat and reflux the mixed solution for 2 hours. After cooling, filter, rinse the filter residue twice with a small amount of ethanol and water mixture (2:1), and then rinse twice with a small amount of water. It is recrystallized and precipitated by hot ethanol and dried at 105 ℃, with a melting point of about 152 ℃. Part of the filtrate from the above test was positive for iron test (IT-19). |
| content analysis | accurately weigh the sample about 500mg, move into a 500ml conical flask, add 25mi,2:3 dilute hydrochloric acid, and heat to boiling. Drop the solution prepared by dissolving 5.6g of stannous chloride in 50ml and 1:2 dilute hydrochloric acid until yellow has faded, and add another 2 drops in excess. The solution is cooled to room temperature in an ice bath, and 8ml of mercury chloride test solution (TS-138) is added and placed for 5min. Add 200ml of water, 25mL 50% dilute sulfuric acid and 4m1 phosphoric acid, add several drops of n-phenanthroline test solution (TS-162), and titrate with 0.1mol/L high cerium sulfate. Cerium sulfate is equivalent to ferrous fumarate (C4H2FeO4)16.99mg per ml0.1mol/L. |
| toxicity | LD503850mg/kg (rat, oral). GRAS(FDA,§ 184.1307d,2000). |
| usage limit | GB 14880-94(mg/kg): 70~150 of cereals and their products; Beverage 30~60; Dairy products, infant food 180~300; Salt and sandwich sugar 1800~3600.GB 2760-2002(mg/100g): Cocoa powder and other nutritious solid beverages, 11-22 (in terms of iron; The amount of equivalent nutritious milk beverage is reduced by dilution ratio); Milk-containing solid beverage 28.9~38. |
| use | ferrous fumarate is used as a food iron fortifier with better absorption effect than inorganic iron. China stipulates that it can be used for salt and sandwich sugar, and the usage amount is 1800~3600 mg/kg; 520~580 mg/kg in high-iron cereals and their products (50g of such foods are limited daily); 180~300 mg/kg in dairy products and infant food; 70~150 mg/kg in cereals and their products; 30~60 mg/kg in beverages. Antianemia drugs are used to treat iron deficiency anemia, and are also widely used in food and feed additives Ferrous fumarate is used as a food iron fortifier, and the absorption effect is better than inorganic iron. China stipulates that it can be used for salt and sandwich sugar, with a usage of 1800-1600mg/kg; 520-580mg/kg in high-iron cereals and their products (50g of such foods are limited daily); 180-300mg/kg in dairy products and infant food; 70-150mg/kg in cereals and their products; 30-60mg/kg in beverages. Nutritional supplement (iron fortifier). Ferrous fumarate is an anti-anemia drug. Anemia is divided into iron deficiency anemia, megaloblastic anemia and aplastic anemia according to different causes. Ferrous fumarate is used to treat iron deficiency anemia. It has high iron content, good absorption, and is difficult to be oxidized into trivalent iron. After taking it, the serum iron value rises quickly and can remain stable. The oral LD50 of mice is 480mg/kg. |
| Production method | It is obtained by replacing sodium fumarate with ferrous sulfate. Heat the water to boiling, add fumaric acid under stirring, and add sodium carbonate to pH = 6.5-6.7. After full stirring, filter while hot to obtain sodium fumarate solution. Add ferrous sulfate solution, stir, heat and reflux for 3-4h, cool and crystallize, and filter. The filter cake is washed with distilled water until the sulfate radical meets the requirements, and dried to obtain ferrous fumarate with 83% yield. It is obtained by the reaction of fumaric acid and iron filings. add 5g of fumaric acid into 100mL of boiling water and neutralize it with sodium carbonate until PH6.5-6.7; Filtration, adding 13g of ferrous sulfate and 100mL of water solution to the obtained disodium fumarate solution, and heating, stirring and refluxing (100 ℃) for 3-4h; Finally, red-brown powder ferrous fumarate 6.2-6.6g was obtained by cooling, crystallization, filtration, washing and drying, with a yield of 85%-90%. add 5g of fumaric acid into 100mL of boiling water and neutralize with sodium carbonate until the Ph value is 6.5-6.7; Filtration, adding 13g of ferrous sulfate and 100mL of water solution to the obtained disodium fumarate solution, heating, stirring and refluxing (100 ℃) for 3-4h; Finally, cooling, crystallization, filtration, washing and drying obtain red-brown powder ferrous fumarate 6.2-6.6g with a yield of 85%-90%. C4H4O4+Na2CO3→C4H2O4Na2+H2O+CO2↑FeSO4+Na2C4H2O4→Na2SO4+FeC4H2O4 |
| category | toxic substances |
| toxicity classification | poisoning |
| acute toxicity | oral administration-rat LD50 3850 mg/kg; Oral administration-mouse LD50: 1570 mg/kg |
| flammability hazard characteristics | combustible; combustion releases smoke stimulated by iron oxide |
| storage and transportation characteristics | warehouse low temperature, ventilation, drying |
| fire extinguishing agent | water, carbon dioxide, dry powder, sand |
Product Packaging：
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage：
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery：
Usually within3-5 working days after full payment.
transport：
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
Packing:
1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);
2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).
3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
P.S.: we accept packaging customization.
Delivery:
1. Stock products are normally shipping within 3 working days.
2. For rush delivery, please contact our sales team for particular arrangement.
Shipping Details:
1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
2. Shipping details & shipping documents will be provided and sent by email.
3. We keep tracking the shippment until clients well received.
4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.
About us
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
FAQ:
1. Are you a trade company or factory
We are a factory with our own trading company.
2.How do you control the quality
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.
3. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
4. Where is your factory located How can I visit the factory
Our factory located in HEBEI, China.
5. Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
6. How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
7. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
8. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
9. How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.