Welcome to LookChem.com Sign In|Join Free

Hebei Nengqian Chemical Import and Export Co., LTD

Assessed Supplier Enterprise Certification

Assessed
Supplier
4th
years
Home>>Products>>2-Deoxy-D-glucose

Product Certification&
Enterprise Certification

More Detail

Hebei Nengqian Chemical Import and Export Co., LTD

Country: China (Mainland)

Business Type:Trading Company

Ms.Sunny

Tel: +86 18732968538

Mobile: +86 18732968538

Tel: +86 18732968538

Fax: 4001020630

URL: https://www.nengqianchemical.com/

Province/state: Hebei

City: Handan

Street: No.1722, Block C, Yangguang Xinzhuo Plaza, 256 Renmin West Road, Fuxing District, Handan City, Hebei Province

MaxCard:


qq
    x
  • Ms.Anna
Contact Suppliers

2-Deoxy-D-glucose

CAS NO.154-17-6

  • FOB Price: USD: 1,630.00-1,800.00 /Metric Ton Get Latest Price
  • Min.Order: 1 Metric Ton
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    Industrial Grade(1-10)Metric TonIndustrial Grade(10-101)Metric TonIndustrial Grade(100-300)Metric Ton

Contact Supplier

Product Details

Keywords

  • D-Glucose, 2-deoxy-
  • 2-deoxyhexopyranose
  • Deoxyglucose

Quick Details

  • ProName: 2-Deoxy-D-glucose 154-17-6
  • CasNo: 154-17-6
  • Molecular Formula: C6H12O5
  • Appearance: White Crystalline Powder
  • Application: This product is for scientific researc...
  • DeliveryTime: 7-15 working days
  • PackAge: Bag/compartments
  • Port: tianjin
  • ProductionCapacity: 200 Metric Ton/Month
  • Purity: 99%
  • Storage: Dry, away from light, sealed.
  • Transportation: We will choose the mode of transportat...
  • LimitNum: 1 Metric Ton
  • color: White powder

Superiority

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements.

Consistent Quality
Our plant has strict quality control in each manufacturing process. Guaranteed.
Meanwhile all the materials are tested before each shipment in our laboratory to double confirm the quality.

Most competitive pricing
Our company is committed to the production and development of titanium dioxide, we always offer the most competitive pricing to customers to help lower their cost in application.

Shortest delivery time
90% of orders are shipped within 7-10 days after receipt of the prepayment or workable L/C.

Respond in 24 hours to inquiry, feedback or other requirements
Our experienced staff is dedicated to answer all of your inquires, feedback or other requirements in 24 hours.

We welcome you to contact us for more information and look forward to working with yo

Details

Product introduction:

Molar Mass 164.16
Density 1.1738 (rough estimate)
Melting Point 146-147°C(lit.)
Boling Point 211.61°C (rough estimate)
Specific Rotation(α) 45.5 º (c=2, H2O)
Flash Point 202.3°C
Water Solubility Soluble in water.
Solubility Soluble in water and ethanol.
Vapor Presure 1.8E-08mmHg at 25°C
Appearance White powder
Color white
Merck 14,2904
BRN 1723331
pKa pK1:12.52 (25°C)
Storage Condition 2-8°C
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Solutions in water are not stable and must be used within 1 working day.
Refractive Index 46.5 ° (C=1, H2O)
MDL MFCD00151328
Use This product is for scientific research only and shall not be used for other purposes.
application 2-deoxy-D-glucose is an inhibitor of glucose metabolism and has been reported to reverse lupus symptoms in mice together with metformin (M258815).
2-deoxy-D-glucose is a derivative of D-glucose. It is an antimetabolite and an important component of orthomyxovirus, paramyxovirus and herpes virus envelope. It can interfere with the synthesis of virus-specific glycoproteins and effectively inhibit the proliferation of herpes monovirus, RNA and DNA envelope virus, breast cancer cells, etc. Antiviral and anti-cancer drugs made of 2-deoxy-D-glucose have been used in clinical treatment research such as herpes monovirus, influenza, AIDS and cancer; anti-aging made of 2-deoxy-D-glucose Cosmetics and medical and health products are also on the market. Therefore, as a drug for the treatment of cancer, viral diseases and anti-aging, 2-deoxy-D-glucose has a wide range of application prospects and a huge market demand.
overview 2-deoxy-D-glucose is an anti-metabolic substance of D-glucose, which has the effects of interfering with the synthesis of virus-specific glycoproteins, inhibiting herpes monovirus, RAN and DNA envelope virus, cancer cell proliferation, etc. At present, antiviral and anticancer drugs prepared from 2-deoxy-D-glucose have been clinically applied to herpes monovirus and cancer treatment, and health products and anti-aging cosmetics prepared from 2-deoxy-D-glucose have also been marketed. 2-DeoxyD-glucose has no toxic side effects, and has a wide range of applications in the fields of medical and health products, anti-aging cosmetics and life science research, with huge market potential and good development prospects.
preparation method a, preparation of intermediates 1.08g of acetoglucosene is dissolved in 5mL of dichloromethane, the ice bath is cooled to 0 ℃ for 15 minutes, then the ice bath is removed, and 0.2mL of hydrogen bromide/acetic acid (HBr/HOAc) solution with a mass percentage concentration of 30% and 10mL of acetic anhydride are added in turn, the selective addition reaction was carried out by stirring at 22 ℃ for 24 hours. After the reaction, anhydrous sodium acetate was added to neutralize until pH = 7, stirring for 20 minutes. After filtration, the solution was swirled under reduced pressure at 25 ℃ and the pressure was 0.1MPa. The obtained solid was recrystallized with 10mL of solvent mixed with petroleum ether and ethyl acetate in a volume ratio of 1:4, then the white solid 2-deoxy-1, 3,4, 6-tetra-O-acetyl-D-glucose 1.30g was prepared by filtration and vacuum drying under reduced pressure with 99% yield. B, synthesis of 2-deoxy-D-glucose 1.0g of the prepared intermediate 2-deoxy-1, 3,4, 6-tetra-O-acetyl-D-glucose is added to 10mL of hydrochloric acid with a concentration of 37% for acid-catalyzed hydrolysis reaction, the reaction temperature is 75 ℃, the reaction time is 4 hours, and the reaction is cooled to room temperature after the end of the reaction, after removing acetyl groups, it is neutralized with 50% (w eight percent) sodium hydroxide solution to pH = 7, then the reaction solution is extracted twice with 10mL methanol solvent, and the extraction solution is combined and then swirled under reduced pressure. The swirled temperature is 28 ℃, and the pressure is 0.1MPa. The obtained solid is recrystallized with 10mL of solvent mixed with methanol and acetone in a volume ratio of 1:1.5, then, after filtration and vacuum drying, a white crystalline solid of 2-deoxy-D-glucose 0.41g was prepared with a yield of 81%.
use is a natural antimetabolite antibiotic, which can inhibit virus infection, yeast fermentation, bacteria and tumor cell growth and other physiological and pharmacological effects. It has antiviral, antibacterial, anti-cancer, anti-epilepsy, anti-aging and other effects. It is used to prevent virus and pathogenic bacteria infection, etc., can prevent infectious diseases caused by HSV, HIV, influenza virus and other pathogenic bacteria, and can treat herpes, etc. It is mainly used for the prevention and treatment of various viral diseases and immunosuppressive diseases of livestock and poultry. It can also be used as an auxiliary treatment for bacterial and mycoplasma infections. It has broad application prospects in medicine and cosmetics industries. Yongzeng chemical, currently mainly used in poultry, veterinary drugs.
2-Deoxy-D-Glucose (2-Deoxy-D-Glucose,2-DG) is a natural antimetabolite antibiotic, which can inhibit virus infection, yeast fermentation, pathogenic bacteria and tumor cell growth.

 

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

 

 

 

 

Our advantages: 

1, High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Product Packaging

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery

Usually within3-5 working days after full payment.

transport

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

FAQ: 
1.Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3.How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5.Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6.How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.