Keywords

• EIDD-2801
• Factory direct sale
• raw material

Quick Details

• ProName: Molnupiravir(EIDD-2801) CAS: 2349386-8...
• CasNo: 2349386-89-4
• Molecular Formula: C13H19N3O7
• Appearance: white powder
• Application: Pharma Grade
• DeliveryTime: 7-10 working day
• PackAge: According yo your request
• Port: Qingdao\Tianjin
• ProductionCapacity: 200 Metric Ton/Day
• Purity: 98%
• Storage: Keep it in dry, cool and ventilated pl...
• Transportation: We will pack and ship according to you...
• LimitNum: 1 Gram
• Moisture Content: 0.01%
• Impurity: 0.1%
• Grade: Pharma Grade

Superiority

【 Product Description 】

Eidd-2801 is an oral bioavailable prodrug of the riboside analogue EIDD-1931. Eidd-2801 has broad spectrum antiviral activity against influenza viruses and multiple coronaviruses such as SARS-COV-2, MERS-CoV, and SARS-COV. Eidd-2801 has the potential to treat COVID-19 as well as seasonal and pandemic influenza.

【 Monabillaway 】

Molnupiravir, also known as EIDD-2801/MK4482, is a riboside analogue that inhibits replication of a variety of RNA viruses, including SARS-COV-2. Eidd-2801 is the oral form of the antiviral compound EIDD-1931; It can be taken as a pill and can be properly absorbed before entering the lungs.

Monabiravir is an oral drug that is activated through metabolism in the body. When it enters the cell, it is converted into rnA-like building blocks. In the first stage, a viral replication machine called RNA polymerase integrates this building block into the SARS-COV-2 RNA genome. However, unlike Remdesivir, which slows viral RNA polymerase, monabilavir does not directly interfere with the function of this viral replication machine. Instead, in the second stage, the RNA-like building blocks are linked to the building blocks of the virus's genetic material. "When the viral RNA is then replicated to make a new virus, it contains many errors, called mutations," said Florian Kabinger, first author of the paper and a doctoral student in Cramer's lab. As a result, the pathogen can no longer proliferate."

The antiviral candidate, Molnupiravir (yellow), is integrated into viral RNA, where it causes mutations (purple) that ultimately prevent the virus from replicating, Pictures from MPI F. Biophysical Chemistry/ Florian Kabinger, Christian Dienemann and Patrick.

Monabilavir also appears to induce mutations in other RNA viruses, preventing them from spreading further. "This compound has the potential to be used to treat many viral diseases," Hobartner said. Monabilave has a lot of potential." This promising drug candidate is currently in phase 3 clinical studies, where it is being tested on a large number of patients. An announcement on whether monabiravir can be safely approved as a drug is likely in the second half of this year. The U.S. government is already optimistic, having recently obtained about 1.7 million doses of Monabiravir, worth more than $1 billion.

[Antiviral]

Eidd-2801 inhibits the replication of several RNA viruses, including SARS-COV-2 (the causative agent of COVID-19), and has been shown to improve lung function, reduce weight loss, and reduce the amount of virus in the lung in animal studies with two different coronaviruses (SARS-COV1 and MERS). In addition to its activity against coronavirus, EIDD-2801 has shown activity in laboratory studies against seasonal influenza, respiratory syncytial virus, Chikungunya virus, Ebola virus, Venezuelan equine encephalitis virus and eastern Equine encephalitis virus.

[In vivo activity]

Eidd-2801 (50-500 mg/kg; Oral; Every 12 hours 3 days) has a strong antiviral effect, can prevent SARS-COV replication and disease.

Pharmacological effects

Eidd-2801 is a compound similar to Remdesivir, and both drugs work by mimicking ribonucleotides, the main building blocks of RNA molecules. When the virus replication, which can be mixed with virus RNA molecules, replace some normal when copy of the original virus nucleic acid base sequence, cause the replication of the virus nucleic acid sequence errors, error accumulation, these fatal sequence is amiss mutation, will eventually stop viral replication, amplification and spread.

[Biological activity]

Molnupiravir (EIDD-2801, MK-4482) is an oral bioactive riboside analogue β -D-N4-hydroxycytidine (NHC; Eidd-1931), exhibiting broad spectrum of antiviral activity against the pathogens of SARS-COV-2, MERS-CoV, SARS-CoV and COVID-19.

Our advantages: 

1) Standard:BP/USP/EP/Enterprise standard1, High quality with competitive price:

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Product Packaging：

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage：

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery：

Usually within3-5 working days after full payment.

transport：

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

Details

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

Typical functions: 
*IMPROVE SLEEP
*MUSCLE BUILDING
*HEALS WOUNDS
* Increased Growth Horm one
* Increased Bone Density
*Better Immune System Function

Our advantages: 

1, High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

2. How do you control the quality   
   Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   
3.  How long is lead time   
   We deliver goods within 3 days for small order, 7-10 days for bulk order.   
4.  Where is your factory located  How can I visit the factory   
    Our factory located in WEIFANG, China. It is only two hours from QINGDAO.  

6. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

7. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

8. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

9. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

10. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.