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Hebei Nengqian Chemical Import and Export Co., LTD

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Hebei Nengqian Chemical Import and Export Co., LTD

Country: China (Mainland)

Business Type:Trading Company

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Tel: +86 18233902561

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Tel: +86 18233902561

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URL: https://www.nengqianchemical.com/

Province/state: Hebei

City: Handan

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thiocolchicine

CAS NO.2730-71-4

  • FOB Price: USD: 45.00-65.00 /Kilogram Get Latest Price
  • Min.Order: 5 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T
  • Available Specifications:

    medical grade(1-50)Kilogrammedical grade(50-500)Kilogram

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Product Details

Keywords

  • Acetamide,N-[5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-,(S)-
  • thiocholchicine
  • Colchicine, 10-thio- (8CI)

Quick Details

  • ProName: thiocolchicine 2730-71-4
  • CasNo: 2730-71-4
  • Molecular Formula: C22H25 N O5 S
  • Appearance: powder
  • Application: Cytosine (C) is one of the four main b...
  • DeliveryTime: 5-7 woking day
  • PackAge: Brown vial or HDPE plastic bottle
  • Port: Qingdao port, Tianjin port
  • ProductionCapacity: 3000 Kilogram/Month
  • Purity: >99%
  • Storage: Cool Dry Place
  • Transportation: Bag or Drum
  • LimitNum: 5 Kilogram
  • packing: According to your request

Superiority

OEM Supply Superior Quality 99% Cytosine CAS 71-30-7

Basic Information:
 

Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).

Cytosine reagent is used in a wide variety of research applications, as an enzyme-substrate or precursor of effector molecules such as cytosine sugars.

Product Name: Cytosine
Synonyms: 4-AMINO-2(1H)-PYRIMIDINONE;4-AMINO-2(1)-PYRIMIDONE;4-AMINO-2-PYRIMIDINOL;4-AMINO-2-OXO-1,2-DIHYDROPYRIMIDINE;4-AMINO-2-HYDROXYPYRIMIDINE;2-Oxy-4-amino pyrimidine;AURORA KA-682;CYTOSINE
CAS: 71-30-7
MF: C4H5N3O
MW: 111.1

 

Details

Molecular Formula C22H25NO5S
Molar Mass 415.5
Density 1.27±0.1 g/cm3(Predicted)
Melting Point 193℃
Boling Point 729.1±60.0 °C(Predicted)
Specific Rotation(α) D20 -221°
Solubility DMSO: soluble10mg/mL, clear
Appearance powder
Color white to beige
pKa 14.75±0.40(Predicted)
Storage Condition -20°C
In vitro study Thiocolchicine is against MCF-7, LoVo, LoVo/DX, A-549 and BALB/3T3 cells with IC 50 values of 0.01 μM, 0.021 μM, 0.398 μM, 0.011 μM and 0.114 μM, respectively.Thiocolchicine (1 nM-100 μM; 24-72 hours) shows a relationship between cell cycle blocking activity and growth inhibition in breast cancer cells. It inhibits cell proliferation of MDA-MB-231 and multidrug resistant (MDR) MCF-7 ADRr breast cancer cells with IC 50 s of 0.6 nM and 400 nM, respectively, as well as MDR CEM-VBL leukemia cells (IC 50 =50 nM).