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Ms.AnnaCAS NO.30045-16-0
medical grade(1-50)Kilogrammedical grade(50-500)Kilogram
OEM Supply Superior Quality 99% Cytosine CAS 71-30-7
Basic Information:
Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).
Cytosine reagent is used in a wide variety of research applications, as an enzyme-substrate or precursor of effector molecules such as cytosine sugars.
| Product Name: | Cytosine |
| Synonyms: | 4-AMINO-2(1H)-PYRIMIDINONE;4-AMINO-2(1)-PYRIMIDONE;4-AMINO-2-PYRIMIDINOL;4-AMINO-2-OXO-1,2-DIHYDROPYRIMIDINE;4-AMINO-2-HYDROXYPYRIMIDINE;2-Oxy-4-amino pyrimidine;AURORA KA-682;CYTOSINE |
| CAS: | 71-30-7 |
| MF: | C4H5N3O |
| MW: | 111.1 |
| Molecular Formula | C22H24NO4 |
| Molar Mass | 366.436 |
| Melting Point | 170-173℃ |
| Solubility | Soluble in acidic solution, insoluble in petroleum ether and other solvents. |
| Appearance | Yellow powder |
| Storage Condition | Inert atmosphere,Room Temperature |
| MDL | MFCD00887635 |
| Physical and Chemical Properties | Yellow needle crystal powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Corydalis, Yuanhu. |
| In vitro study | Dehydrocorydaline (0-200 μM) treatment significantly inhibits the growth of MCF-7 cells in a dose-dependent manner. The cell viability is decreased by approximate 40% after 24 h of 200 μM Dehydrocorydaline. Dehydrocorydaline (0-200 μM)dose-dependently increases Bax protein expression and decreases Bcl-2 protein expression. Dehydrocorydaline (0-200 μM)induces activation of caspase-7,-8 and the cleavage of PARP without affecting caspase-9. |
| In vivo study | Dehydrocorydaline manifests a low acute toxicity with an LD 50 of about 277.5±19.0 mg/kg body weight in mice following oral administration and 21.1±1.4 mg/kg for intraperitoneal injection. |