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Hebei Nengqian Chemical Import and Export Co., LTD

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Home>>Products>>Oral Light Yellow Isotretinoin Raw Powder Quality Delivery Guaranteed for Accutane CAS: 4759-48-2.

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Hebei Nengqian Chemical Import and Export Co., LTD

Country: China (Mainland)

Business Type:Trading Company

Mr.cui

Tel: +86 13910575315

Ms.Anna

Tel: 19831957301

Mr.Jacky

Tel: 15632927689

Ms.Winnie

Tel: 18233902561

Ms.Mandy

Tel: 19903295909

Ms.Chris

Tel: +86 16630923639

Ms.Sunny

Tel: 18732968538

Mr.Bailey

Tel: +86 15383190639

Mobile: +86 15632927689

Tel: +86 13910575315

Fax: 0310-8698866

URL: http://hbnq1.com/

Province/state: Hebei

City: Xingtai

Street: hebei

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Oral Light Yellow Isotretinoin Raw Powder Quality Delivery Guaranteed for Accutane CAS: 4759-48-2.

CAS NO.4759-48-2

  • FOB Price: USD: 1.00-5.00 /Gram Get Latest Price
  • Min.Order: 1 Gram
  • Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
  • Available Specifications:

    Pharmaceutical intermedia(1-5)GramPharmaceutical intermedia(5-10)Gram

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Product Details

Keywords

  • Isotretinoin
  • 13-cis-vitamin a acid
  • (L)-ISOTRETINOIN

Quick Details

  • ProName: Oral Light Yellow Isotretinoin Raw Pow...
  • CasNo: 4759-48-2
  • Molecular Formula: C20H28O2
  • Appearance: white powder
  • Application: Pharmaceutical Intermediates
  • DeliveryTime: 7-10 working day
  • PackAge: According yo your request
  • Port: Qingdao\Tianjin
  • ProductionCapacity: 200 Metric Ton/Day
  • Purity: 99%
  • Storage: Keep it in dry, cool and ventilated pl...
  • Transportation: We will package and transport accordin...
  • LimitNum: 1 Gram
  • Grade: Industrial Grade,Pharma Grade

Superiority

Describtion:
What is Isotretinoin
Isotretinoin belongs to the first generation of vitamin A acid. It is a stereoisomer of all-trans vitamin A acid. Oral administration has an anti-oil effect which has special effect on severe acne. The mechanism is as follows:
 
Application:
1. it can reduce sebaceous gland and inhibit the activity of sebaceous gland, reducing the effect of secretion of the sebaceous glands, thus inhibiting the growth of Propionibacterium which relies on lipid environment.
2. it has an anti-keratosis effect, can inhibit the excess proliferation of epidermal and promote its differentiation. It also reduces the keratosis of hair follicles and the catheter of sebaceous glands.
3. it can also affect the function of lymphocytes and monocytes, and inhibit the chemotaxis of neutrophil, and thus having anti-inflammatory activity.
4. it can exert its therapeutic effect by selectively binding Vitamin A acid nuclear receptors. It can inhibit the proliferation of acne rod bacilli. Moreover it has effects of immunity stimulation at low doses, but has immunity suppression effect at high doses.
5. It can inhibit the biogenesis of collagenase and gelatinase in the skin, and can also inhibit the activity of ornithine decarboxylase. Owing to the major role of ornithine decarboxylase in inducing skin mutations, so isotretinoin can also suppress tumorigenesis.
6. when subjects to topical administration, it has a similar mechanism of action as vitamin A acid which induces the proliferation of epidermal cell, promotes the differentiation of epidermal cell granular layer into the stratum corneum. It can also regulate the horny plug occurring during some abnormal cornification processes of Hair follicle sebaceous epithelium, and thus playing a therapeutic role.
 

Certifications

 

Item   Spec. Result
Appearance   A yellow or light-orange,
Crystalline powder
Yellow crystalline powder
Identification   The IR adsorption spectrum should correspond with reference spectrum conform
    Should exhibits maximum absorption at 352mm conform
Loss on drying   ≤0.5% 0.07%
Residue on ignition   ≤0.1% 0.03%
Heavy metals   ≤0.002% <0.002%
Related substances
(Reporting threshold 0.05%)
Isotretinoin ≤5.0% <0.04%
  Impurity G ≤0.2% <0.05%
  Single unknown impurity ≤0.10% RRT≈0.91<0.05%
  Total impurities
(Except Isotretinoin)
≤0.5% 0.01%
Residual solvents Acetaldehyd ≤15ppm <15ppm
  Ethyl acetat ≤5000ppm 865ppm
Microbiological limit tests Bacteria ≤100CFU/g <20CFU/g
  Molds and yeasts ≤100CFU/g <20CFU/g
  Staphylococcus aureus and P.aeruginosa  
Absent
Absent
Assay   98.0%~102.0%(dried substance) 99.6%
Conclusion   Conform to USP40


 

 

 

Our advantages: 

1, High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

  1. How do you control the quality   
    Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   
  2.  How long is lead time   
    We deliver goods within 3 days for small order, 7-10 days for bulk order.   
  3.  Where is your factory located  How can I visit the factory   
     Our factory located in WEIFANG, China. It is only two hours from QINGDAO.  


6. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 


7. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  


8. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

9. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

10. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.

 

 

Details

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  


Our advantages: 

1, High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

  1. How do you control the quality   
    Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   
  2.  How long is lead time   
    We deliver goods within 3 days for small order, 7-10 days for bulk order.   
  3.  Where is your factory located  How can I visit the factory   
     Our factory located in WEIFANG, China. It is only two hours from QINGDAO.  


6. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 


7. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  


8. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

9. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

10. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.