Hebei Nengqian Chemical Import and Export Co., LTD
Assessed Supplier Enterprise Certification
- Assessed
Supplier - 4th
years
Assessed Supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: 86-139-10575315
Tel: +86 15632961819
Tel: +86 18233902561
Tel: +86 15717685612
Tel: +86 16630923639
Tel: +86 18732968538
Tel: +86 18833033983
Tel: +86 19831957301
Mobile: +86 19831957301
Tel: 86-139-10575315
Fax: 4001020630
URL: https://www.nengqianchemical.com/
Province/state: Hebei
City: Handan
Street: Congtai District, La Defense North
MaxCard:
Ms.AnnaCAS NO.480-44-4
Pharmaceutical grade(1-50)KilogramPharmaceutical grade(51-99)Kilogram
Our Advantage
Rich Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.
Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.
24 hour service
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
| Molar Mass | 284.26 |
| Density | 1.2160 (rough estimate) |
| Melting Point | 260-265°C(lit.) |
| Boling Point | 346.76°C (rough estimate) |
| Flash Point | 198.2°C |
| Solubility | Soluble in hot ethanol, insoluble in ether, soluble in alkaline solution. |
| Vapor Presure | 2.25E-11mmHg at 25°C |
| Appearance | Yellow needle crystal |
| Color | Light Yellow to Green-Yellow to Dark Yellow |
| Maximum wavelength(λmax) | ['335nm(EtOH)(lit.)'] |
| Merck | 14,13 |
| BRN | 277879 |
| pKa | 6.51±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.6200 (estimate) |
| MDL | MFCD00016936 |
| Physical and Chemical Properties | Yellow needle-like crystals, soluble in methanol, ethanol, DMSO and other organic solvents, from eupatorium, Thistle, Acacia. |
| plant source: | chrysanthemum |
| Plant source | Acacia farnesiana (Linn.) Willd.) (Mimosa) Leguminosae. Shrubs, 2-4 m high; branches with spines, spines up to 1-2cm long. Two pinnate compound leaves, pinna 4-8 pairs, each pinna 10-20 pairs of leaflets, small leaves linear oblong. The flower heads are axillary, 1.5cm in diameter, often in clusters. The pod is cylindrical, 3-7cm long and 8-15mm in diameter. Seeds are mostly black. The flowers are extremely fragrant for extracting essence. Thorn irrigation or small trees, two pinnate compound leaves, flower heads clustered in leaf axils, when in full bloom, like golden pompoms. |
| biological activity | Acacetin (5,7-Dihydroxy-4 '-methoxyflavone) is an orally effective flavonoid from Tephroseris kirilowii (Turcz.) Holub. Acacetin stopped in the ATP binding pocket of PI3Kγ. Acacetin leads to arrest of cancer cell cycle and induces apoptosis and autophagy. Acacetin has effective anti-cancer and anti-inflammatory activities and has the potential to be used in the research of pain-related diseases. |
| Cell Line: | Breast cancer MCF-7 cells, hepatocellular carcinoma SMMC-7721 cells, lung adenocarcinoma A549 cells, esophageal carcinoma Eca109 cells MDA-MB-231 cells MDA-MB-231 cells MDA-MB-231 cells MDA-MB-231 cells |
| Concentration: | 10, 20, 40, 60, 80, 100, 150, 200 μM 50, 100, 150 μM 50, 100, 150 μM 50, 100, 150 μM 50, 100, 150 μM |
| Incubation Time: | 24 hours 24 hours 24 hours 24 hours 24 hours |
| Result: | Decreased cancer cell viabilities in a dose-dependent manner. Had IC 50 values of 82.75 μM, 103.9 μM, 157.4 μM, 54.7 μM in MDA-MB-231, MCF-7, A549, Eca109 cells, respectively. Resulted in increase in percentage of cells at G2/M phase and decrease in percentage of cells at G1 and S phase in a dose-dependent manner. Induced apoptosis. Induced autophagy. Resulted in marked increases in EGFP-LC3 puncta formation and a dose-dependent accumulation of LC3-II. Resulted in decrease in levels of Bcl-2 and Bcl-xL and increase in levels of p53. Led to decreases in levels of PI3Kγ-p110, p-AKT, p-mTOR, p-p70S6K, and p-ULK in a dose-dependent manner. Had little or no effect on expression of PI3Kα, PI3Kβ, PI3Kδ, p-ERK, p-p38, and p-JNK. Significantly suppressed microglial activation in an LPS-induced (ip; 5mg/kg) neuroinflammation mouse model. |
| Animal Model: | Male C57BL/6 mice, 7 weeks of age |
| Dosage: | 5, 20 mg/kg |
| Administration: | Orally; once a day for 3 days |
| use | acacia has sedative and anti-cancer effects. used for content determination/identification/pharmacological experiment, etc. Pharmacological effects: the effects of relaxing depression, rationing qi, calming the nerves, and activating collaterals. |
Product Packaging：
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage：
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery：
Usually within3-5 working days after full payment.
transport：
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
Packing:
1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);
2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).
3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
P.S.: we accept packaging customization.
Delivery:
1. Stock products are normally shipping within 3 working days.
2. For rush delivery, please contact our sales team for particular arrangement.
Shipping Details:
1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
2. Shipping details & shipping documents will be provided and sent by email.
3. We keep tracking the shippment until clients well received.
4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.
About us
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
FAQ:
1. Are you a trade company or factory
We are a factory with our own trading company.
2.How do you control the quality
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.
3. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
4. Where is your factory located How can I visit the factory
Our factory located in HEBEI, China.
5. Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
6. How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
7. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
8. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
9. How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.