Hebei Nengqian Chemical Import and Export Co., LTD
Assessed Supplier Enterprise Certification
- Assessed
Supplier - 4th
years
Assessed Supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: +86 18732968538
Mobile: +86 18732968538
Tel: +86 18732968538
Fax: 4001020630
URL: https://www.nengqianchemical.com/
Province/state: Hebei
City: Handan
Street: No.1722, Block C, Yangguang Xinzhuo Plaza, 256 Renmin West Road, Fuxing District, Handan City, Hebei Province
MaxCard:
Ms.AnnaCAS NO.481-72-1
Pharmaceutical grade(1-50)KilogramPharmaceutical grade(51-99)Kilogram
Our Advantage
Rich Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.
Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.
24 hour service
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
| Molecular Formula | C15H10O5 |
| Molar Mass | 270.24 |
| Density | 1.3280 (rough estimate) |
| Melting Point | 223-224°C |
| Boling Point | 373.35°C (rough estimate) |
| Flash Point | 311.9°C |
| Solubility | Soluble in acetaldehyde, benzene, hot ethanol, dilute ammonia, sodium carbonate and sodium hydroxide aqueous solutions. Soluble in hot ethanol. It is yellow in ether and benzene, and crimson in ammonia and sulfuric acid. |
| Vapor Presure | 8.9E-14mmHg at 25°C |
| Appearance | Orange needle crystal (toluene), or khaki crystal powder. |
| Color | Orange to Dark Orange |
| Merck | 14,306 |
| BRN | 2059062 |
| pKa | 6.30±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Hygroscopic |
| Refractive Index | 1.5000 (estimate) |
| MDL | MFCD00017373 |
| Physical and Chemical Properties | Soluble in acetaldehyde, benzene, hot ethanol, dilute ammonia, sodium carbonate and sodium hydroxide aqueous solution. Soluble in hot ethanol. In ether and benzene was yellow, ammonia and sulfuric acid showed a red. Rhizome derived from Polygonaceae plant Rheum palmatum L. |
| plant source: | aloe |
| Efficacy and role | Aloe-emodin is the antibacterial active ingredient of rhubarb. It is an orange needle-like crystal (toluene) or khaki crystal powder Chemical items, aloe-emodin can be extracted from aloe. Aloe-emodin has many benefits to human health, with anti-tumor activity, antibacterial activity, immunosuppressive effect, and purgative effect, now widely used as raw materials for medicines and cosmetics. Anti-tumor effect: In recent years, scholars at home and abroad have been interested in the anti-tumor effect of aloe-emodin. Its main anti-tumor activity is concentrated in neuroectodermal tumors, liver cancer, lung squamous cell carcinoma, skin Merkel cell carcinoma, gastric cancer, leukemia and other tumors, and has a wide range of anti-cancer. Aloe-emodin has an inhibitory effect on P388 leukemia cells and can prolong survival. One of its mechanisms is to inhibit the biosynthesis of DNA, RNA and protein in cancer cells. antibacterial activity: at the concentration of 1.5~25 mg/ml, aloe-emodin has inhibitory effect on staphylococcus, streptococcus, diphtheria bacillus, Bacillus subtilis, anthrax, paratyphoid bacillus, dysentery bacillus, etc., among which staphylococcus and streptococcus are the most sensitive, and the effective concentration of bacteriostasis is 15-25ug/ml. The inhibitory concentrations of Staphylococcus aureus 209P, Escherichia coli and Shigella flexneri in vitro were 7.5mg/L and 600mg/L respectively, and their antibacterial effects were antibacterial rather than bactericidal. One of its mechanisms of action is to inhibit electron transfer in mitochondrial respiratory chain. Aloe-emodin has a strong inhibitory effect on nucleic acid and protein synthesis of Staphylococcus aureus. Aloe-emodin has a strong inhibitory effect on common anaerobic bacteria in clinic, among which it can inhibit the growth of 90% ~ 100% strains on common fragile bacilli, and its MIC is slightly higher than metronidazole. Anaerobic bacteria of 76% ~ 91% can be inhibited at a concentration of 8 μg/ml. immunosuppressive effect: aloe-emodin can inhibit the production of biological antibodies, inhibit the ability of carbon particle clearance, reduce the weight of immune organs, reduce the number of white blood cells, and reduce the function of peritoneal macrophages. In vitro concentration of 100 μg/ml has obvious inhibitory effect on [3H]-TDR and [3H]Urd entering lymphocytes. purgative effect: aloe-emodin has strong purgative activity, intestinal bacteria metabolize aloe-emodin, rhein, rhein anthrone, the latter has strong purgative effect. It is clinically used as a laxative and has the effects of increasing appetite and laxative of the large intestine. According to foreign medical reports, aloin is hydrolyzed into aloe-emodin under the action of parasitic bacteria in the human body. This aloe-emodin stimulates the peristalsis of the intestinal wall. At the same time, due to changes in osmotic pressure, it is conducive to the elimination of waste in the intestinal tract. So as to achieve irritation and laxation, this stimulating and laxative effect has a special effect on constipation and hemorrhoids. Especially for middle-aged and elderly constipation, the treatment effect is more obvious. |
| rhubarb | rhubarb is a commonly used Chinese medicine. It was first published in "Shen Nong's Materia Medica" and listed as inferior. Materia Medica has been recorded in the past dynasties. Rhubarb is the dry root and rhizome of the Polygonaceae plant, the palm-leaved rhubarb, the Tanggu extra yellow or the medicinal rhubarb Rheum officinale Baill. Mainly produced in Sichuan, Gansu, Qinghai and other places. Rhubarb has the effects of purging heat and clearing the intestines, cooling blood and detoxifying, removing blood stasis and dredging the meridian. It is used for constipation with real heat, accumulated abdominal pain, diarrhea and dysentery, damp-heat jaundice, blood-heat vomiting, red eyes, pharyngeal swelling, intestinal carbuncle Abdominal pain, carbuncle swelling, boils, blood stasis, amenorrhea, and bruises. External treatment of water and fire burns, upper gastrointestinal bleeding, etc. Can be used raw or roasted, steamed or fried charcoal. Rhubarb has antibacterial effect on most Gram-positive bacteria and some Gram-negative bacteria in test tubes. The active ingredients are mainly anthraquinone derivatives, among which aloe-emodin, emodin and rhein have the best effect. it has inhibitory effect on mouse leukemia P388: rhein, emodin and aloe emodin were extracted from rhubarb. These three anthraquinone derivatives all reduce the amount of ascites and the number of cancer cells in tumor mice to varying degrees. Among them, the effect of rhein is more obvious, and aloe-emodin is worse, which is basically parallel to prolonging survival. Rhein and emodin have strong inhibitory effects on DNA, RNA and protein biosynthesis, while aloe-emodin has weak inhibitory effects. fig. 1 is Baill, a medicinal rhubarb Rheum officinale. |
| biological activity | Aloe-emodin (NSC 38628, Rhabarberone) is an interferon inducer that acts on JEV,IC50 is 1 μg/mL, EV71,IC50 is 0.33 μg/mL. |
| use | used for content determination/identification/pharmacological experiments, etc. Pharmacological effects: It has anti-tumor activity, antibacterial activity, immunosuppressive effect, and purgative effect. It is now widely used as raw materials for medicines and cosmetics. |
Product Packaging：
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage：
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery：
Usually within3-5 working days after full payment.
transport：
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
Packing:
1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);
2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).
3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
P.S.: we accept packaging customization.
Delivery:
1. Stock products are normally shipping within 3 working days.
2. For rush delivery, please contact our sales team for particular arrangement.
Shipping Details:
1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
2. Shipping details & shipping documents will be provided and sent by email.
3. We keep tracking the shippment until clients well received.
4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.
About us
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
FAQ:
1. Are you a trade company or factory
We are a factory with our own trading company.
2.How do you control the quality
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.
3. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
4. Where is your factory located How can I visit the factory
Our factory located in HEBEI, China.
5. Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
6. How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
7. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
8. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
9. How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.