Hebei Nengqian Chemical Import and Export Co., LTD
Assessed Supplier Enterprise Certification
- Assessed
Supplier - 4th
years
Assessed Supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: +86 18233902561
Mobile: +86 18233902561
Tel: +86 18233902561
Fax: 4001020630
URL: https://www.nengqianchemical.com/
Province/state: Hebei
City: Handan
Street: No.1722, Block C, Yangguang Xinzhuo Plaza, 256 Renmin West Road, Fuxing District, Handan City, Hebei Province
MaxCard:
Ms.AnnaCAS NO.51333-22-3
medical grade(1-50)Metric Tonmedical grade(50-500)Metric Ton
Our Advantage
Rich Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.
Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.
24 hour service
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.
| Molecular Formula | C25H34O6 |
| Molar Mass | 430.53 |
| Density | 1.1046 (rough estimate) |
| Melting Point | 221-232°C (dec.) |
| Boling Point | 464.79°C (rough estimate) |
| Specific Rotation(α) | D25 +98.9° (c = 0.28 in methylene chloride) |
| Flash Point | 201.8°C |
| Water Solubility | 21.53mg/L(temperature not stated) |
| Solubility | Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in ethanol (96 per cent). |
| Vapor Presure | 6.94E-17mmHg at 25°C |
| Appearance | powder |
| Color | White to Off-White |
| Merck | 14,1468 |
| pKa | 12.87±0.10(Predicted) |
| Storage Condition | Store at RT |
| Refractive Index | 1.4593 (estimate) |
| Use | [Drug Name] generic name: Budesonide Nasal Spray [indications] prevention and treatment of perennial and seasonal allergic rhinitis, can also be used for vasomotor rhinitis. [specification] 32 g/spray; 120 spray per bottle, the concentration of the solution is 0.64mg/ml [dosage] Nasal Spray: Left hand spray right nostril, right hand spray left nostril, avoid spraying directly to the nasal septum. Adult: Initially 2 sprays in each nostril, once in the morning and once in the evening. The maximum daily dosage should not exceed 8 sprays (256 g). After the symptoms were relieved, 1 spray was given to each nostril once a day. children over 6 years of age: same as adults. [adverse reactions] About 5% of patients will occur local stimulation of adverse reactions. common (> 100/1): airway: local irritation, mild bloody discharge, Epistaxis. Rare (1000/2): systemic: angioedema. Skin: urticaria, rash, dermatitis, pruritus. airway: perforation of nasal septum and mucosal ulcer. immediate or delayed allergic reactions, including urticaria, rash, dermatitis, angioedema, and pruritus, have been reported. Very few patients develop mucosal ulceration and septal perforation after intranasal administration of corticosteroids. The cause of these adverse effects, which may be caused by glucocorticoids, these diseases, or other factors, is unknown. [Precautions] 1. After 14 days of using this product, the symptoms have not improved, please refer to Counseling doctor. 2. Self-treatment should not exceed 3 months, If need more than 3 months, should be used under the guidance of a physician. 3. Long-term use of high doses, may occur systemic effects of glucocorticoids. Long-term treatment of children and adolescents, may cause growth retardation, should be used under the guidance of a physician. 4. With nasal fungal infection and herpes patients with caution. 5. Use of systemic corticosteroids to switch to the use of this product, should be used under the guidance of a physician. 6. Pulmonary tuberculosis patients with caution. 7. This product is only used in nasal cavity, and should not contact the eyes. If it contacts the eyes, please wash with water immediately. 8.6 children under the age of this product is not recommended. 9. Pregnant and lactating women should avoid using this product. 10. Use with caution in athletes. 11. In case of overdose or serious adverse reactions, medical attention should be taken immediately. 12. It is contraindicated for those who are allergic to this product, and it should be used with caution for those with allergic constitution. 13. The use of this product is prohibited when the character is changed. 14. Please keep this product out of contact with children. 15. Children must use under adult supervision. 16. If you are using other drugs, please refer to Counseling physician or pharmacist before using this product. [drug interaction] 1. Combination with ketoconazole should be avoided. 2. If concomitant use with other drugs may cause drug interaction, please contact Counseling physician or pharmacist for details. [Pharmacology and Toxicology] This product is a glucocorticoid drug, with strong local anti-inflammatory and anti-allergic effects. |
| In vitro study | In human bronchial epithelial cell lines BEAS-2B and primary human bronchial epithelial cells, Budesonide potently inhibits the production of eotaxin and RANTES proteins, although Budesonide inhibits the expression of the chemokine mRNA. Budesonide also inhibits the activity of reporter genes driven by RANTES-and chemokine promoters. Budesonide also selectively accelerates the decay of chemokines and MCP-4 mRNA. Budesonide time-and protein synthesis-dependently decreases VEGF secretion and VEGF mRNA expression in human bronchial epithelial cell lines BEAS-2B and primary human bronchial epithelial cells, and these effects were inhibited by the corticosteroid receptor antagonist mifeprisone (RU 486), suggesting that Budesonide reduces the secretion of VEGF through its glucocorticoid receptor-mediated effects. Budesonide dose-dependently almost completely inhibited pig dust-induced release of IL-6 and IL-8 in epithelial cells and LPS-induced release of IL-6 and TNF-α in alveolar macrophages. |
| In vivo study | In rats, Budesonide completely inhibited LPS at low concentration (2.5 mg/ml/kg) and high concentration (50 mg/mL/kg) induced TNF-α, interleukin (IL)-1beta,IL-6 and production of monocyte chemoattractant protein (MCP)-1. In A/J mice, Budesonide exerts chemoprevention, growth arrest by Mad2/3, and apoptosis by Bim/Blk and caspase-8/9. |
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
Superiority
As a reliable partner for Chinese market, we are specialized in chemical raw materials; consolidate sourcing, marketing, sales, distribution and after-sale services, providing our partners with sourcing evaluation, technology supports, toll/contract manufacture, investment solution and suitable partnership establishment in China.
Service we can provide:
1. provide costomers with "one-stop"packaging service,from manufacture ,research,development,production,export and so on
2. Quality control, before shipment.
3. Prompt shipment with professional documents
4. Packing as your request, with photo before shipment
5.Mix and different products in ONE PCL,increase the working efficiency for customers.
6.We can export from many China main ports,convenient for the customes provide logistics services.
Our advantages:
1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
Product Packaging：
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage：
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery：
Usually within3-5 working days after full payment.
transport：
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
FAQ:
1.Are you a trade company or factory
We are a factory with our own trading company.
2.How do you control the quality
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.
3.How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
4. Where is your factory located How can I visit the factory
Our factory located in HEBEI, China.
5.Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
6.How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
7. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
8. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
9.How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.