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Hebei Nengqian Chemical Import and Export Co., LTD

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Hebei Nengqian Chemical Import and Export Co., LTD

Country: China (Mainland)

Business Type:Trading Company

Mr.cui

Tel: +86 13910575315

Ms.Anna

Tel: +86 19831957301

Mr.Jacky

Tel: +86 15632927689

Ms.Winnie

Tel: +86 18233902561

Ms.Mandy

Tel: +86 19903295909

Ms.Chris

Tel: +86 16630923639

Ms.Sunny

Tel: +86 18732968538

Mr.Bailey

Tel: +86 15383190639

Mobile: +86 19831957301

Tel: +86 13910575315

Fax: 0310-8698866

URL: http://hbnq1.com/

Province/state: Hebei

City: Handan

Street: Congtai District, La Defense North

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Magnolol

CAS NO.528-43-8

  • FOB Price: USD: 1.00-10.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    Pharmaceutical grade(1-50)KilogramPharmaceutical grade(51-99)Kilogram

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Product Details

Keywords

  • 2,2'-Bichavicol(6CI)
  • 2,2'-Biphenyldiol, 5,5'-diallyl- (8CI)
  • Magnolia officinalis Rehd.et Wils

Quick Details

  • ProName: Magnolol 528-43-8
  • CasNo: 528-43-8
  • Molecular Formula: C18H18O2
  • Appearance: White
  • Application: used for content determination/identif...
  • DeliveryTime: 7-10 working days
  • PackAge: In plastic outside weave or according ...
  • Port: port of Qingdao、port of Tianjin
  • ProductionCapacity: 500 Kilogram/Week
  • Purity: >99%
  • Storage: -15°C
  • Transportation: We ship goods via DHL, Fedex, UPS, TNT...
  • LimitNum: 1 Kilogram
  • Grade: Industrial Grade,Food Grade,Pharma Gra...
  • Shelf Life: Two years

Superiority

Our Advantage 

Rich Experience 
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. 

Quality service 
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product. 
  
24 hour service 
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage. 

High quality 
Dedicated to serving customers first, we provide reasonable prices, high quality products. 

 

Details

Our advantage:

1. High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Molecular Formula C18H18O2
Molar Mass 266.33
Density 1.107±0.06 g/cm3(Predicted)
Melting Point 101.5-102°
Boling Point 180°C/1mmHg(lit.)
Flash Point 184.5°C
JECFA Number 2023
Solubility Soluble in benzene, ether, chloroform, acetone and commonly used organic solvents, difficult to dissolve in water.
Vapor Presure 5.25E-07mmHg at 25°C
Appearance Colorless needle crystal
Color White to Almost white
Maximum wavelength(λmax) ['292nm(EtOH)(lit.)']
Merck 14,5697
pKa 9.49±0.43(Predicted)
Storage Condition Sealed in dry,2-8°C
Refractive Index 1.601
MDL MFCD00016658
Physical and Chemical Properties Soluble in benzene, ether, chloroform, acetone and commonly used organic solvents, difficult to dissolve in water. Magnolia magnolias official Rehd. et Wils.

 

Plant source: Magnolia officinalis
FEMA 4559 | MAGNOLOL
plant extract magnolol is officinalis Rehd. et Wills from Magnoliaceae (Magnoliaceae) plant Magnolia Magnolia. And Magnolia officinalis Rehd. et Wills. var. biloba Rehd. et Wills. An active substance extracted from dry skin, branch skin and root skin has antibacterial, anti-inflammatory, anti-tumor, anti-endomycin, muscle relaxation, and relief of acute inflammatory pain. In terms of antibacterial effect, magnolol has significant antibacterial activity against Gram-positive bacteria, acid-resistant bacteria and filamentous fungi, has more significant antibacterial effect against Streptococcus mutans, and has the strongest inhibitory effect on Staphylococcus. Clinically, it is mainly used to eliminate chest and abdomen fullness, calm the central nervous system, athlete muscle relaxation, antifungal, anti-ulcer and other drugs.
[Habitat and Distribution] It often grows in the foothills of hillsides at an altitude of 800~1700 meters and in the mixed woods beside streams. It is a light-loving native tree species; it likes cool and humid climate. Slightly acidic or neutral soil with deep, fertile, loose, humus-rich and well-drained soil is appropriate. Mainly produced in Enshi, Jianshi, Badong, Yichang, Lichuan in Hubei Province and Chengkou, Kaixian, Wuxi, Wushan, Shizhu, Wulong, Fengjie in Chongqing. Chongqing Yunyang, Wanzhou, Zhongxian, Fengdu, Fuling, Jiangjin, Qianjiang, Pengshui, Xiushan, Nanchuan and other places are also distributed.
[plant morphology] deciduous trees, 7~15m high. The bark is purple-brown, the winter buds are covered by stipules, and the stipules fall off after opening. Single leaves alternate, gathered at the top of branchlets, the leaves are elliptic and obovate, 20 ~ 45cm long, 10 ~ 25cm wide, the apex is obtuse or short-pointed, the base is cuneate or round, the entire or microwave-shaped, and the back When young, it is gray-white and short tomentose, and when old, it is white and powdery. Flowers and leaves open at the same time, single branch tops, white, fragrant, about 15cm in diameter, stout pedicel, covered with brown hairs; tepals 9~12; many stamens; pistil carpels many, arranged on the extended torus. Aggregate fruit ovate-elliptic, woody, with 1 seed per chamber. The flowering period is from April to May and the fruiting period is from September to October.
Figure 1 is Magnolia officinalis
application Magnolia officinalis total phenol is a phenolic mixture extracted from traditional Chinese medicine Magnolia officinalis, which has many biological functions such as antiviral, antibacterial, anti-inflammatory and anti-diarrhea, while the antioxidant effect of Magnolia officinalis total phenol is an important basis for its biological function.
pharmacological action magnolol is a diphenylpropyl compound, white to yellowish brown powder, fragrant, spicy and slightly bitter. it is the main active ingredient of magnolia officinalis, and is a small molecular natural product extracted from dry dry skin, root skin and branch skin of magnolia officinalis or magnolia officinalis of magnolia family, it has the effects of anti-inflammatory, antibacterial, protecting cardiovascular and cerebrovascular system, anti-anxiety and depression, muscle relaxation, anti-oxidation, improving gastrointestinal dysfunction and anti-tumor.
The water extract of Magnolia officinalis has a significant arrow poison-like effect. Its alcohol extract can reduce the grip strength and has a strong inhibitory effect on spasms induced by drugs such as strychnine and diprotoxin. It can relieve the intestinal spasm caused by barium chloride and pilocarpine, and has an inhibitory effect on the contraction of isolated guinea pig bronchial smooth muscle caused by histamine. A water-soluble alkaloid was isolated from Magnolia officinalis-Magnolia officinalis (also known as Magnolia curarine) has a relaxing effect on striated muscle and can block the transmission of impulses on the motor endplate, so it is a nerve-muscle block effect.
honokiol has antibacterial effects on gram-positive bacteria such as staphylococcus, pneumococcus, hemolytic streptococcus and gram-negative bacilli such as dysentery bacillus, typhoid bacillus, Escherichia coli and Bacillus subtilis.
The ether extract of Magnolia officinalis can reduce the spontaneous activity of mice and resist the excitement caused by methamphetamine or apomorphine. Magnolol and isobalokiol also have significant central inhibitory effects. Magnolol can completely inhibit spinal cord reflex in mice, and ether extract 0.25~1 g/kg can show central inhibition that any reflex disappears.
Magnolia officinalis Shengpin and Jiang Zhipin have anti-gastric ulcer effect on rat pyloric ligation type and stress type 2 acute experimental gastric ulcer model, especially ginger products have stronger effect. With magnolol 100mg/kg intraperitoneal injection or subcutaneous injection, water immersion bound stress ulcer disease, mercaptoethylamine ulcer, pyloric ligation ulcer have inhibitory effect, but also can antagonize the role of central gastric acid secretion stimulant.
use used for content determination/identification/pharmacological experiments, etc. Pharmacological effects: Magnolol has obvious and long-lasting central muscle relaxation, central nervous system inhibition, anti-inflammatory, antibacterial, anti-pathogenic microorganisms, anti-ulcer, anti-oxidation, anti-tumor, inhibit morphine withdrawal reaction, can inhibit Platelet aggregation and other pharmacological effects, magnolol is used to treat acute enteritis. Bacterial or amoebic dysentery. Chronic gastritis, etc. Among them, in terms of antibacterial effect, magnolol has significant antibacterial activity against Gram-positive bacteria, acid-resistant bacteria and filamentous fungi, has more significant antibacterial effect against Streptococcus mutans, and has the strongest inhibitory effect on Staphylococcus. Clinically, it is mainly used to eliminate chest and abdomen fullness, calm the central nervous system, athlete muscle relaxation, antifungal, anti-ulcer and other drugs.
It has antifungal, antibacterial and antioxidant bioactive substances, and has anti-inflammatory activity by interfering with NF -κB signaling.

 

 

Product Packaging

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery

Usually within3-5 working days after full payment.

transport

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

 

Packing:  
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg); 

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg). 

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg). 

P.S.: we accept packaging customization. 


  
Delivery:   

  1. Stock products are normally shipping within 3 working days.  

  2. For rush delivery, please contact our sales team for particular arrangement. 

Shipping Details: 
  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker. 

  2. Shipping details & shipping documents will be provided and sent by email. 

  3. We keep tracking the shippment until clients well received. 

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

About us

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3. How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.