Product Certification&
Enterprise Certification
Country: China (Mainland)
Business Type:Trading Company
Tel: 86-139-10575315
Tel: +86 15632961819
Tel: +86 18233902561
Tel: +86 15717685612
Tel: +86 16630923639
Tel: +86 18732968538
Tel: +86 18833033983
Tel: +86 19831957301
Mobile: +86 19831957301
Tel: 86-139-10575315
Fax: 4001020630
URL: https://www.nengqianchemical.com/
Province/state: Hebei
City: Handan
Street: Congtai District, La Defense North
MaxCard:
CAS NO.57-67-0
Pharmaceutical grade(1-50)KilogramPharmaceutical grade(51-99)Kilogram
Our Advantage
Rich Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.
Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.
24 hour service
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
Molar Mass | 214.24 |
Density | 1.3916 (rough estimate) |
Melting Point | 190-193°C |
Boling Point | 426.1±47.0 °C(Predicted) |
Flash Point | 249.2°C |
Water Solubility | 1g/1000mL at 25 ºC |
Solubility | Almost insoluble in water, slightly soluble in ethanol, easily soluble in acetone, methanol and dilute inorganic acid. |
Vapor Presure | 1.09E-09mmHg at 25°C |
Appearance | White or yellowish crystalline powder |
Color | white to off-white |
Merck | 14,8908 |
BRN | 2695326 |
pKa | pKa 2.37(H2Ot = 37) (Uncertain) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Stability | Stable. Incompatible with strong oxidizing agents. |
Sensitive | Sensitive to light |
Refractive Index | 1.6440 (estimate) |
MDL | MFCD00038136 |
Physical and Chemical Properties | White or yellowish crystalline powder, odorless, slightly bitter, melting point 176~181 ℃. Almost insoluble in water, slightly soluble in ethanol, soluble in acetone, methanol and dilute inorganic acid. Can change color under light. |
Use | The preferred drug for the treatment of leprosy, suitable for the treatment of various types of leprosy, can improve the clinical symptoms. General mucosal lesions improved faster, skin lesions improved more slowly, neuropathy is slower, so long course of treatment, easy to produce drug resistance, not easy to cure, in addition, also available for the treatment of dermatitis herpetiformis, lupus erythematosus, psoriasis, foot disease and malaria. The formulation is a tablet. |
trait | sulfamidine is white needle-like crystalline powder, odorless or almost odorless, tasteless. It was gradually changed in light. The melting point was 189-192 °c. This product is dissolved in boiling water, slightly soluble in water, ethanol or acetone. Soluble in dilute hydrochloric acid. Insoluble in sodium hydroxide solution. |
purpose | sulfamidine is a low-grade sulfa drug that can inhibit bacteria. It is mainly used for the production of sulfadiazine, sulfadimidine and other higher sulfonamides. sulfonamides, used for bacillary dysentery, enteritis, etc. The drug of first choice for the treatment of leprosy, suitable for the treatment of various types of leprosy, can improve the clinical symptoms. General mucosal lesions improved faster, skin lesions improved more slowly, neuropathy is slower, so long course of treatment, easy to produce drug resistance, not easy to cure, in addition, also available for the treatment of dermatitis herpetiformis, lupus erythematosus, psoriasis, foot disease and malaria. The formulation is a tablet. This strain of sulfonamides is used for intestinal antibacterial infections, such as bacillary dysentery enteritis, and can also be used to prevent infection before intestinal surgery. In the pharmaceutical industry, it is generally used as an important raw material for SM2,SD and other sulfadiazine drugs. |
sulfanilamide | sulfanilamide and sulfamidine were commonly used sulfanilamide drugs. Due to their high toxicity, they were generally not used as preferred drugs, both of them and acetaminophen sulfonyl chloride are now used only as intermediates in the production of sulfonamides. sulfamidine, also known as sulfamidine and Zhili tablets, is the earliest sulfanilamide used for intestinal infection. The molecular structure of sulfamidine has a strong basic guanidine group, with high dissociation degree and low fat solubility, after oral administration, although there is a certain amount of absorption from the intestinal tract, but not enough to achieve effective blood concentration, it is not used for systemic infection. But can maintain a higher concentration in the intestine, more for bacterial infections of the digestive tract. Such as gastroenteritis, dysentery, etc. When combined with trimethoprim (TMP) or ditrimethoprim (DVD), the antibacterial effect is significantly enhanced. preparation method: 1. Sulfanilamide and guanidine nitrate can be melted in soda ash and condensed under reduced pressure to obtain sulfamidine product. 2, obtained by reacting acesulfame chloride with guanidine nitrate in the presence of sodium hydroxide in a mixed solution of acetone and water. 3, p-aminobenzenesulfonyl chloride was synthesized from p-nitrobenzenesulfonyl chloride by catalytic hydrogenation, Then ammoniation is carried out to produce sulfanilamide, and then reaction with guanidine nitrate to obtain sulfamidine. Drug Interaction: 1, at the same time, the application of urine alkalizing drugs can enhance the solubility of this product in alkaline urine and increase the excretion. 2, sulfamidine can not be combined with P-aminobenzoic acid, P-aminobenzoic acid can replace this product by bacterial uptake, both antagonistic. It is also unsuitable for use in combination with local anesthetics containing p-Aminobenzoyl, such as procaine, tetracaine, and the like. 3, for those taking estrogenic contraceptives, simultaneous prolonged use of sulfamidine can lead to a decrease in the reliability of contraception and increase the chance of bleeding outside the menstrual period. 4, the additive effect of photosensitivity may occur when combined with photosensitive drugs. 5. The requirement of vitamin K is increased in those who receive this product. |
production method | the sulfonamide is obtained by condensation with guanidine nitrate. |
category | toxic substances |
toxicity grade | poisoning |
Acute toxicity | intraperitoneal-mouse LDL0: 500 mg/kg |
flammability hazard characteristics | flammability; Toxic nitrogen oxide and sulfur oxide fumes from combustion |
storage and transportation characteristics | warehouse ventilation and low temperature drying |
extinguishing agent | dry powder, foam, sand, carbon dioxide, water mist |
Product Packaging:
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage:
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery:
Usually within3-5 working days after full payment.
transport:
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
Packing:
1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);
2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).
3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
P.S.: we accept packaging customization.
Delivery:
1. Stock products are normally shipping within 3 working days.
2. For rush delivery, please contact our sales team for particular arrangement.
Shipping Details:
1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
2. Shipping details & shipping documents will be provided and sent by email.
3. We keep tracking the shippment until clients well received.
4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.
About us
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
FAQ:
1. Are you a trade company or factory
We are a factory with our own trading company.
2.How do you control the quality
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.
3. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
4. Where is your factory located How can I visit the factory
Our factory located in HEBEI, China.
5. Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
6. How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
7. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
8. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
9. How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.