Hebei Nengqian Chemical Import and Export Co., LTD
Assessed Supplier Enterprise Certification
- Assessed
Supplier - 4th
years
Assessed Supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: +86 18233902561
Mobile: +86 18233902561
Tel: +86 18233902561
Fax: 4001020630
URL: https://www.nengqianchemical.com/
Province/state: Hebei
City: Handan
Street: No.1722, Block C, Yangguang Xinzhuo Plaza, 256 Renmin West Road, Fuxing District, Handan City, Hebei Province
MaxCard:
Ms.AnnaCAS NO.59865-13-3
Pharmaceutical grade(1-5)KilogramPharmaceutical grade(6-99)Kilogram
Our advantages:
1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
| Molecular Formula | C62H111N11O12 |
| Molar Mass | 1202.61 |
| Density | 1.016g/cm3 |
| Melting Point | 151°C |
| Boling Point | 1293.8°C at 760 mmHg |
| Specific Rotation(α) | D20 -244° (c = 0.6 in chloroform); D20 -189° (c = 0.5 in methano |
| Flash Point | 736.3°C |
| Solubility | Soluble in methanol, ethanol, acetone, ether or chloroform, slightly soluble in water |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White needle crystal |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.467 |
| MDL | MFCD00274558 |
| Use | For the treatment of leukemia, cancer, kidney transplantation, tuberculosis, etc |
| In vitro study | Cyclosporine induces phenotypic transformation through cell-autonomous mechanisms, including infiltration of non-transformed cells. Treatment of tumor cells with Cyclosporine resulted in significant morphological changes, including fluctuations in cell membrane margins and numerous pseudopodia protrusions, increased cell motility, and matrix-independent (infiltrative) growth. Cyclosporine (CsA) has potent immunosuppressive properties, suggesting its role in blocking cytokine gene transcription in activated T cells. Cyclosporine inhibits the phosphatase activity of calcineurin by forming a complex with cyclophilin, which regulates nuclear transport and subsequent activation of NFAT transcription factors. Cyclosporine also blocks the activation of JNK and p38 caused by antigen recognition, making CsA a highly specific inhibitor of T cell activation. Cyclosporine-mediated inhibition of biliary excretion of MPAG via the Mrp2 transporter is a reactive mechanism of interaction between Cyclosporine and mycophenate mofetil (MMF). Cyclosporine inhibits the biochemical and morphological differentiation of skeletal muscle cells and has minimal effect on proliferation. |
| In vivo study | Cyclosporine enhances tumor growth in immunodeficient SCID light brown mice. Cyclosporine inhibits induced post-traumatic muscle regeneration in mice. Cyclosporine reached the highest concentration at 1H in blood, spleen, and kidney, with higher concentrations in spleen and kidney than in blood. |
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
FAQ:
1. Are you a trade company or factory
We are a factory with our own trading company.
6. Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
7. How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
8. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
9. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
10. How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.