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Hebei Nengqian Chemical Import and Export Co., LTD

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Hebei Nengqian Chemical Import and Export Co., LTD

Country: China (Mainland)

Business Type:Trading Company

Ms.Sunny

Tel: +86 18732968538

Mobile: +86 18732968538

Tel: +86 18732968538

Fax: 4001020630

URL: https://www.nengqianchemical.com/

Province/state: Hebei

City: Handan

Street: Congtai District, La Defense North

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N-Acetyl-L-cysteine

CAS NO.616-91-1

  • FOB Price: USD: 1.00-10.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    Pharmaceutical grade(1-50)KilogramPharmaceutical grade(51-99)Kilogram

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Product Details

Keywords

  • Sodium 2-acetamido-3-mercaptopropionate
  • (S)-ALPHA-AMINO-2-NAPHTHALENEPROPIONIC ACID
  • Mucolytikum Lappe

Quick Details

  • ProName: N-Acetyl-L-cysteine 616-91-1
  • CasNo: 616-91-1
  • Molecular Formula: C5H9NO3S
  • Appearance: White
  • Application: This product is for scientific researc...
  • DeliveryTime: 7-10 working days
  • PackAge: In plastic outside weave or according ...
  • Port: port of Qingdao、port of Tianjin
  • ProductionCapacity: 500 Kilogram/Week
  • Purity: >99%
  • Storage: -15°C
  • Transportation: We ship goods via DHL, Fedex, UPS, TNT...
  • LimitNum: 1 Kilogram
  • Shelf Life: Two years

Superiority

Our Advantage 

Rich Experience 
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. 

Quality service 
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product. 
  
24 hour service 
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage. 

High quality 
Dedicated to serving customers first, we provide reasonable prices, high quality products. 

 

Details

Our advantage:

1. High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Molecular Formula C5H9NO3S
Molar Mass 163.19
Density 1.249 (estimate)
Melting Point 106-108°C(lit.)
Boling Point 407.7±40.0 °C(Predicted)
Specific Rotation(α) -35.1 ºC (c=2,H2O)
Flash Point 200.4°C
Water Solubility Soluble in water, ethanol, methanol, dimethyl sulfoxide, hot isopropyl alcohol, methyl acetate and ethyl acetate. Insoluble in chloroform and ether.
Solubility Soluble in water and ethanol
Vapor Presure 0Pa at 20℃
Appearance White crystal
Color White
Merck 14,88
BRN 1724426
pKa pK1: 9.52 (30°C)
Storage Condition 2-8°C
Stability Stable. Incompatible with strong oxidizing agents.
Refractive Index 24 ° (C=JPC Method)
MDL MFCD00004880
Physical and Chemical Properties N-acetyl-L-cysteine white crystalline powder with garlic-like odor, sour. Hygroscopic, soluble in water or ethanol, insoluble in ether, chloroform. In aqueous solution was acidic (10g/L H2O pH2-2.75),mp101-107. This product is an N-acetylated derivative of cysteine, containing sulfhydryl group in the molecule, which can break the disulfide bond (-S-S-) of the mucin peptide bond, thus turning the mucin chain into a small molecule peptide chain, reduce the viscosity of mucin, therefore, this product is mucilaginous, purulent sputum, respiratory tract mucus dissolution drugs.
Use This product is for scientific research only and shall not be used for other purposes.
Target ROS/ROS1 TNF-α

This product contains acetylcysteine (CsH9NQS) should be labeled 90.0% ~ 110.0%.

trait

This product is soluble fine particles; Gas fragrance.

identification

  1. take an appropriate amount of this product (about equivalent to acetylcysteine 0.2g), add water to dissolve 20ml, adjust the pH value to 6.5 with 1 mol/L sodium hydroxide solution, and dilute to 40ml with water as the test solution; another 0.2g of acetylcysteine control substance was taken and prepared by the same method as the control substance solution. According to the thin layer chromatography (General 0502) test, absorb the above two solutions each 5fil, respectively point on the same silica gel G thin | Layer plate, with n-butanol-glacial acetic acid-water (4 : 1 : 5) the upper layer liquid mixed and equilibrated for 10 minutes is the developing agent. After spreading, it is taken out, dried under hot air flow, and then colored in iodine vapor, the position and color of the main spot displayed by the test solution should be the same as that of the reference solution.
  2. in the chromatogram recorded under the content determination item, the retention time of the main peak of the test solution should be consistent with the retention time of the main peak of the reference solution. The above (1), (2) two items can be done one.

examination

  1. acidity take this product, add water to dissolve and dilute to make 10% of the solution, according to the law (General 0631),p H value should be 2.0~3.0.
  2. weight loss on drying: take this product at 70T: dry for 4 hours, and the weight loss shall not exceed 2.0% (General rule 0831).
  3. Related substances take an appropriate amount of fine powder of this product (about 25mg of acetylcysteine), weigh it accurately, put it in a 25ml measuring flask, add mobile phase to dissolve and dilute to the scale, shake well, filter, the continuous filtrate was taken as the test solution; 1ml was accurately measured, placed in a 100ml measuring flask, diluted to the scale with the mobile phase, and shaken, as a control solution.
  4. According to high performance liquid chromatography (General 0512), silica gel bonded with a Eighteen alkyl silane was used as a filler; Ammonium sulfate buffer (2.25g of ammonium sulfate, sodium heptane sulfonate 1. 82G, diluted to ML with water, adjusted to pH 1.4 with 7mol/L hydrochloric acid solution)-methanol (90: 10) as mobile phase; Detection wavelength was 205nm. The number of theoretical plates is not less than 1000 based on the acetyl cysteine peak. The control solution and the test solution were respectively injected into the human liquid chromatograph, and the chromatogram was recorded to 3 times of the retention time of the main component peak. If there are impurity peaks in the chromatogram of the test solution, the peak area of a single impurity shall not be greater than the main peak area of the control solution (1. 0), the sum of each impurity peak area shall not be greater than 1 of the main peak area of the control solution. 5 times (1. 5).
  5. other than the particle size, should comply with the relevant provisions under The granule (General Principles 0104).

containing the most measured

measured by high performance liquid chromatography (General 0512).

  1. chromatographic conditions and system suitability test using eighteen alkyl silane bonded silica as filler; 0. 05mol/L two potassium hydrogen phosphate solution (with phosphoric acid to adjust the pH value to 3.0) as the mobile phase; The detection wavelength was 214mn. The number of theoretical plates is not less than 1000 based on the acetyl cysteine peak.
  2. determine 10 bags of this product, transfer the whole content to a 500ml measuring flask, add an appropriate amount of sodium metabisulfite solution (1-2000), shake to dissolve and dilute to the scale, shake well, take 25ml and place lOOmKO.lg specification) or 200ml(0. 2G specification) in the measuring flask, dilute to the scale with sodium metabisulfite solution (1-2000), shake well, filter, take the continued filtrate as the test solution, and inject 20fJ into the human liquid chromatograph with precision, record the chromatogram; Take about 50mg of acetylcysteine reference substance, weigh it accurately, put it in a 100ml measuring flask, add sodium metabisulfite solution (1-2000) to dissolve and dilute to the scale, shake well, and use it as the reference solution. According to the external standard method to calculate the peak area, that is.

Product Packaging

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery

Usually within3-5 working days after full payment.

transport

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

 

Packing:  
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg); 

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg). 

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg). 

P.S.: we accept packaging customization. 


  
Delivery:   

  1. Stock products are normally shipping within 3 working days.  

  2. For rush delivery, please contact our sales team for particular arrangement. 

Shipping Details: 
  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker. 

  2. Shipping details & shipping documents will be provided and sent by email. 

  3. We keep tracking the shippment until clients well received. 

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

About us

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3. How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.