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Hebei Nengqian Chemical Import and Export Co., LTD

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Hebei Nengqian Chemical Import and Export Co., LTD

Country: China (Mainland)

Business Type:Trading Company

Ms.Sunny

Tel: +86 18732968538

Mobile: +86 18732968538

Tel: +86 18732968538

Fax: 4001020630

URL: https://www.nengqianchemical.com/

Province/state: Hebei

City: Handan

Street: No.1722, Block C, Yangguang Xinzhuo Plaza, 256 Renmin West Road, Fuxing District, Handan City, Hebei Province

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Oxaliplatin 61825-94-3

CAS NO.61825-94-3

  • FOB Price: USD: 5.00-10.00 /Metric Ton Get Latest Price
  • Min.Order: 1 Metric Ton
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    1(1-25)Metric Ton1(50-99)Metric Ton

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Product Details

Keywords

  • trans-l-diaminocyclohexane oxalatoplatinum
  • [SP-4-2-(1R-TRANS)]-(1,2-CYCLOHEXANEDIAMINE-N,N')[ETHANEDIOATA(2-)-O,O']PLATINUM
  • oxalato(1r,2r-cyclohexanediammine)platinum(ii)

Quick Details

  • ProName: Oxaliplatin 61825-94-3
  • CasNo: 61825-94-3
  • Molecular Formula: C8H12N2O4Pt
  • Appearance: White to Almost white
  • Application: Antitumor drug used to treat rectal ca...
  • DeliveryTime: 5 to 10 business days
  • PackAge: Factory default package
  • Port: Tianjin Port or Qingdao Port
  • ProductionCapacity: 100 Metric Ton/Month
  • Purity: 99%
  • Storage: 2-8°C
  • Transportation: We will deliver the goods according to...
  • LimitNum: 1 Metric Ton

Superiority

Our advantages:

1. High quality and competitive price:

1) Standard: BP/USP/EP/ enterprise standard

2) All purity 鈮 9%

3) We are manufacturers and can provide high quality products at factory prices.

2. Fast and safe delivery

1) The package can be sent within 24 hours of payment. A tracking number is available

2) Safe and prudent shipment. Multiple modes of transportation are available for you to choose from.

3) Clearance rate 鈮 9%

4) We have our own agents/resellers/distributors who can help us ship our products very quickly and safely,

We have stock to transfer.

Our services:
1. Fast delivery: We can deliver within 24 hours after receiving your payment.
2. Quality can be promised. It sells well all over the world.
3. Payment terms: T/T, , t/t
4. Always provide free samples.
5. Keep track of your orders. Keep you informed of further updates on your order.
6. Packaging: Professional packaging, professional materials.


Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary drug intermediates, dye intermediates, pigments, cosmetic raw materials and chemical reagents.

Our company has a group of sales team, service and information feedback vertical integration of perfect marketing network, products are sold all over the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, service as the fundamental, quality of survival, technology and development, adhere to the quality first, fair price, good customer service awareness and responsibility. In the future, Hebei Can Import and Export Trade Co., Ltd. will always uphold the business philosophy of "integrity and innovation", achieve integrity management, and keep moving forward on the road of specialization and internationalization!

Are you a trading company or a factory We are a factory with our own trading company.


How do you control quality
Our factory is equipped with professional technical personnel to control the quality, every 2 hours with external inspectors sampling test, to ensure the quality of our production. We are also subject to BV, SGS or any other third party inspection.
How long is the delivery time
We can deliver small orders within 3 days and large orders within 7-10 days.
Where is your factory How can I visit the factory
Our factory is located in Weifang, China. Only two hours' drive from Qingdao.

6. Can I have some samples
Yes, we can provide free samples, but the freight will be paid by our customers.


7. How to start an order or pay After confirming the order will first send a proforma invoice with our bank details attached. Pay by T/T
,


8. How to confirm product quality before placing an order
You can get samples of some products for free, you just need to pay for shipping or arrange to have them delivered to us and picked up.
You can send us your product specifications and requirements and we will manufacture the products according to your requirements.

9. What is the time of delivery

We ship small orders within 3 days and large orders within 7-10 days.

Details

 

Product Description


High Quality Oxaliplati n CAS 61825-94 3 Treatment Of Rectal Cancer
Product Name:    Oxaliplati n
Synonyms:    [SP-4-2-(1R-TRANS)]-(1,2-CYCLOHEXANEDIAMINE-N,N')[ETHANEDIOATA(2-)-O,O']PLATINUM;OXALIPLATI N;trans-l-diaminocyclohexane oxalatoplatinum;(1,2-cyclohexanediamine-n,n')(ethanedioato(2-)-o,o')-platinu(sp-4-2-(1r-tr;1-ohp;oxalato(1r,2r-cyclohexanediammine)platinum(ii);oxalatoplatin;[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N,)[ethanedioato(2-)-O,O'Jplatinum
CAS:    61825-94 3
MF:    C8H12N2O4Pt
MW:    395.28
EINECS:    621-248-1
Product Categories:    Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;Antineoplastic;Inhibitors;APIs;Amines;Heterocycles;chemical reaction,pharm,electronic,materials;PRAXILENE;API
Mol File:    61825-94 3.mol


Oxaliplati n is a second generation platinum drug prepared in three steps from either k2tCl4 or K2Ptl4. It has an antitumor spectrum similar to cisplati n, however, it is more effective against L1210 leukemia and cisplati n resistant L1210. It is also effective against B16 melanoma but has a dose limiting toxicity of peripheral sensory neuropathy that is reversible upon cessation of the drug. The (R,R)- enantiomer has greater activity than the (S,S)-isomer but this is tumor line dependent, e.g., there was no difference found for P-388 or Sarcoma 180. Clinical drug administration based on circadium timing showed it was better tolerated when given 16 h after the onset of light. Oxaliplati n binds to guanineN7 and can lead to bidentate chelation that results in the bending of DNA. This feature is recognized by high mobility group proteins (HMG) which impedes repair reactions and stops replication and transcription.

Oxaliplati n CAS 61825-94 3 of Chemical Properties
alpha     +74.5-78.0 (D/20)(c=0.5,H2O)
storage temp.     2-8°C
solubility     Slightly soluble in water, very slightly soluble in methan ol, practically insoluble in anhydrous ethanol.
form     solid
color     White to Almost white
Water Solubility     Soluble in water with heating and/or sonication
Merck     14,6912
Stability:    Stable. Store cool. Incompatible with oxidizing agents.
InChIKey    ZROHGHOFXNOHSO-BNTLRKBRSA-L
CAS DataBase Reference    61825-94 3

Function and Application of Oxaliplati n CAS 61825-94 3
1. Third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.
2. A potent anti-neoplastic agent that binds to DNA and shows efficacy in Cisplati n resistant cell lines
3. Oxaliplati n is a platinum-based antineoplastic agent that functions by forming DNA adducts specifically in cancer cells, preventing DNA replication and transcription which leads to cell death. Oxaliplati n has cytotoxic effects in a broad range of cell lines, including colon, ovarian, and lung cancer, with IC50 values ranging from 0.5-240, 0.12-19.8, and 2.6-6.1 μM, respectively. Through its general cytotoxic effects, oxaliplati n has anti-tumor activity against advanced colorectal cancer and is typically administered with fluorourac il and leucovorin in a combination known as FOLFOX.

Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.

Shipping Terms
By Express By Air By Sea
Suitable for under 50kg
Fast:3-4 days
High cost
Door to door service
Easy to pick up the goods
Suitable for more than 50kg
Fast:3-4 days
High cost
Airport to airport
Professional broker needed
Suitable for more than 500kg
Slow:15-30 days
Low cost
Port to port
Professional broker needed

 

Package

 

 

  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg); 

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg). 

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg). 

P.S.: we accept packaging customization. 

 

Delivery
  1. Stock products are normally shipping within 3 working days.  

  2. For rush delivery, please contact our sales team for particular arrangement. 

Shipping Details: 
  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker. 

  2. Shipping details & shipping documents will be provided and sent by email. 

  3. We keep tracking the shippment until clients well received. 

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

 

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

 

  

    

Our advantages:

Hebei Nengqian Chemical Import and Export Co., LTD.. is located in xingtai City, Hebei Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.
 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. Reasonable & competitive price, fast lead time.

5. Sample is available for your evaluation & Formulation development.

6. Faster delivery:Sample order in stock and 3-7 days for bulk production.

7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.

8. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.                                                    

 

 

 

 

 

 

 

 

 

 

 

 

 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

  1. How do you control the quality   
    Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   
  2.  How long is lead time  
    We deliver goods within 3 days for small order, 7-10 days for bulk order.   
  3.  Where is your factory located How can I visit the factory   
     Our factory located in WEIFANG, China. It is only two hours from QINGDAO.  


6. Can i get some samples 
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 


7. How to start orders or make payments 
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  


8. How to confirm the Product Quality before placing orders 
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

9. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

10. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.

 

 

 

 

 

 

 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

  1. How do you control the quality   
    Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   
  2.  How long is lead time  
    We deliver goods within 3 days for small order, 7-10 days for bulk order.   
  3.  Where is your factory located How can I visit the factory   
     Our factory located in WEIFANG, China. It is only two hours from QINGDAO.  


6. Can i get some samples 
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 


7. How to start orders or make payments 
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  


8. How to confirm the Product Quality before placing orders 
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

9. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

10. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.