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Hebei Nengqian Chemical Import and Export Co., LTD

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Hebei Nengqian Chemical Import and Export Co., LTD

Country: China (Mainland)

Business Type:Trading Company

Mr.cui

Tel: 86-139-10575315

Mr.Jacky

Tel: +86 15632961819

Ms.Winnie

Tel: +86 18233902561

Ms.Mandy

Tel: +86 15717685612

Ms.Chris

Tel: +86 16630923639

Ms.Sunny

Tel: +86 18732968538

Ms.Bailey

Tel: +86 18833033983

Ms.Anna

Tel: +86 19831957301

Mobile: +86 19831957301

Tel: 86-139-10575315

Fax: 4001020630

URL: https://www.nengqianchemical.com/

Province/state: Hebei

City: Handan

Street: Congtai District, La Defense North

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1-Adamantanamine hydrochloride

CAS NO.665-66-7

  • FOB Price: USD: 1,630.00-1,800.00 /Metric Ton Get Latest Price
  • Min.Order: 1 Metric Ton
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    Industrial Grade(1-10)Metric TonIndustrial Grade(10-101)Metric TonIndustrial Grade(100-300)Metric Ton

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Product Details

Keywords

  • 1-Adamantanamine HCl
  • 1-Aminoadamantane HydrochlorideAmantadine Hydrochloride
  • 1-Adamantanamine,hydrochloride (8CI)

Quick Details

  • ProName: 1-Adamantanamine hydrochloride 665-...
  • CasNo: 665-66-7
  • Molecular Formula: C10H18ClN
  • Appearance: White Crystalline Powder
  • Application: Anti-Virus drug, belonging to narrow s...
  • DeliveryTime: 7-15 working days
  • PackAge: Bag/compartments
  • Port: tianjin
  • ProductionCapacity: 200 Metric Ton/Month
  • Purity: 99%
  • Storage: Dry, away from light, sealed.
  • Transportation: We will choose the mode of transportat...
  • LimitNum: 1 Metric Ton
  • color: White powder

Superiority

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements.

Consistent Quality
Our plant has strict quality control in each manufacturing process. Guaranteed.
Meanwhile all the materials are tested before each shipment in our laboratory to double confirm the quality.

Most competitive pricing
Our company is committed to the production and development of titanium dioxide, we always offer the most competitive pricing to customers to help lower their cost in application.

Shortest delivery time
90% of orders are shipped within 7-10 days after receipt of the prepayment or workable L/C.

Respond in 24 hours to inquiry, feedback or other requirements
Our experienced staff is dedicated to answer all of your inquires, feedback or other requirements in 24 hours.

We welcome you to contact us for more information and look forward to working with yo

Details

Product introduction:

Molar Mass 187.71
Density 1.0276 (rough estimate)
Melting Point >300°C(lit.)
Boling Point 308.63°C (rough estimate)
Flash Point 95.974°C
Water Solubility soluble
Solubility H2O: 50mg/mL
Vapor Presure 0.085mmHg at 25°C
Appearance White crystal
Color White
Merck 14,374
BRN 4198854
Storage Condition Store below +30°C.
Sensitive Hygroscopic
Refractive Index 1.6100 (estimate)
MDL MFCD00074723
Physical and Chemical Properties Melting point 300°C
water-soluble soluble
Use Used as an antiviral drug

Related substances

take this product about l. Add 5mol/L sodium hydroxide solution (20ml) and trichloromethane (18ml) to the separating funnel, shake for 10 minutes, let stand and separate into layers, take the three-gas methane layer, shake and dehydrate with appropriate amount of anhydrous sodium sulfate, and filter, take the filtrate and put it in a 20ml measuring flask, dilute it to the scale with chloroform, and shake it up to be used as a test solution. Take about 0.5g of the adamantane reference substance, put it in a 10ml measuring flask, dissolve it with three gases of methane and dilute it to the scale, shake it well, take 1ml of the solution, put it in a ml measuring flask, and add 1ml of the test solution, dilute to the scale with chloroform and shake well as a system-suitable solution. According to the gas chromatography method (General 0521) test, the capillary column with 5% phenyl-95% methyl polysiloxane (or similar polarity) as the stationary liquid is used as the column; The initial temperature is 70°C, and the maintenance time is 5 minutes, the temperature was raised to 250°C at a rate of 10°C per minute for 17 minutes; The inlet temperature was 220°C; And the detector temperature was 300°C. Take the system applicable solution 2 u1 and inject it into the gas chromatograph. The separation degree of amantadine peak and adamantane peak should be greater than 20, and the signal-to-noise ratio of amantadine peak height should be greater than 30. The sample solution 2u1 was accurately measured and injected into human gas chromatograph, and the chromatogram was recorded. If there are impurity peaks in the chromatogram of the test solution, the area of a single impurity peak shall not be more than 0.3% of the total peak area, and the sum of each impurity peak area shall not be more than 1.0% of the total peak area, calculated by the normalization method.

loss on drying

take this product, dry to constant weight at 105°C, weight loss shall not exceed 0.5% (General rule 0831).

ignition residue

not more than 0.1% (General rule 0841).

Heavy metals

take 2.0g of this product, add 23ml of water to dissolve, add 2ml of acetate buffer (pH 3.5), and check according to law (General rule 0821 first law), containing heavy metals not more than 5 parts per million.

Use Anti-Virus drug, belonging to narrow spectrum, is only used for the prevention and treatment of influenza caused by type A2 Virus. The product prevents Virus of the penetration into the host cell, and affects Virus of the shell, to inhibit Virus of the proliferation. This product is used as an anti-paralysis drug. May promote dopamine release.
amantadine hydrochloride is used as an antiviral agent; The product is used as an anti-paralytic agent. May promote dopamine release.
for the synthesis of anti-Virus drug intermediate, which has the effect of preventing and treating type A2 influenza
This product prevents Virus from penetrating into host cells and affects Virus of The unshelled, virus inhibition of proliferation. May promote dopamine release.
Virus was prevented from penetrating into the host cell, and Virus was affected to decoat, and Virus proliferation was inhibited. May promote dopamine release.
production method It is obtained by salt formation and purification of amantadine. Amantadine, distilled water and activated carbon were added to the glass enamel. Hydrochloric acid was added to adjust the pH to 3-5, heated to 70 °c for half an hour to dissolve the decolorizing, cooled to room temperature, and filtered. The filtrate was pumped into a reduced-pressure concentration tank, concentrated in (14.7kPa) to the shape of a porridge, naturally cooled, and filtered. Acetone was added to soak and rinse to pH 5, filtered and dried at 70 ° C. To obtain amantadine hydrochloride.
category toxic substances
toxicity grade poisoning
Acute toxicity oral-rat LD50: 800 mg/kg; Oral-mouse LD50: 700 mg/kg
flammability hazard characteristics toxic nitrogen oxides and hydrogen chloride smoke produced by combustion; Food: Fantasy, elation, excitement, dream
storage and transportation characteristics ventilation and low temperature drying
fire extinguishing agent dry powder, foam, sand, carbon dioxide, water mist

 

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

Our company has a number of sales team, service and information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

 

 

 

 

Our advantages: 

1, High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Product Packaging

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery

Usually within3-5 working days after full payment.

transport

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

FAQ: 
1.Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3.How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5.Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6.How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.