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Hebei Nengqian Chemical Import and Export Co., LTD

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Hebei Nengqian Chemical Import and Export Co., LTD

Country: China (Mainland)

Business Type:Trading Company

Ms.Sunny

Tel: +86 18732968538

Mobile: +86 18732968538

Tel: +86 18732968538

Fax: 4001020630

URL: https://www.nengqianchemical.com/

Province/state: Hebei

City: Handan

Street: No.1722, Block C, Yangguang Xinzhuo Plaza, 256 Renmin West Road, Fuxing District, Handan City, Hebei Province

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Sulfadiazine

CAS NO.68-35-9

  • FOB Price: USD: 1.00-10.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    Pharmaceutical grade(1-50)KilogramPharmaceutical grade(51-99)Kilogram

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Product Details

Keywords

  • Sulfanilamide,N1-2(1H)-pyrimidinylidene- (6CI)
  • Eksadiazine;
  • 4-azanyl-N-pyrimidin-2-yl-benzenesulfonamide

Quick Details

  • ProName: Sulfadiazine 68-35-9
  • CasNo: 68-35-9
  • Molecular Formula: C10H10N4O2S
  • Appearance: White
  • Application: Sulfonamides for the treatment of infe...
  • DeliveryTime: 7-10 working days
  • PackAge: In plastic outside weave or according ...
  • Port: port of Qingdao、port of Tianjin
  • ProductionCapacity: 500 Kilogram/Week
  • Purity: >99%
  • Storage: -15°C
  • Transportation: We ship goods via DHL, Fedex, UPS, TNT...
  • LimitNum: 1 Kilogram
  • Shelf Life: Two years

Superiority

Our Advantage 

Rich Experience 
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. 

Quality service 
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product. 
  
24 hour service 
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage. 

High quality 
Dedicated to serving customers first, we provide reasonable prices, high quality products. 

 

Details

Our advantage:

1. High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Molar Mass 250.28
Density 1.3780 (rough estimate)
Melting Point 253 °C (dec.) (lit.)
Boling Point 512.6±52.0 °C(Predicted)
Water Solubility 67.13mg/L(25 ºC)
Solubility Almost insoluble in water, slightly soluble in ethanol or acetone, easily soluble in dilute hydrochloric acid, sodium hydroxide solution or ammonia solution
Appearance powder or crystals(white to faint yellow, faint pink)
Color white
Merck 14,8903
BRN 6733588
pKa pKa 2.21(H2Ot = 25I = 0.5 (NaCl)) (Uncertain)
Storage Condition 2-8°C
Sensitive Sensitive to light
Refractive Index 1.6440 (estimate)
MDL MFCD00006065
Physical and Chemical Properties White or off-white crystals or powders. Melting point 252-256 °c. Almost insoluble in water, at 37 C, pH = 5.6 water solubility of 13mg/100ml,pH = 7.5 water solubility of 200mg/100ml. Slightly soluble in ethanol or acetone, soluble in dilute hydrochloric acid, sodium hydroxide solution or ammonia solution, odorless, tasteless, light gradient dark.
Use Sulfonamides for the treatment of infections caused by hemolytic streptococci, Pneumonia cocci, meningococci, Neisseria gonorrhoeae, E. Coli

 Compound sulfadiazine tablets

Authoritative Data Verified Data

This product contains sulfadiazine (C10H10N402S) and trimethoprim (C14H18N403) should be labeled with the amount of 90.0% ~ 110.0%.

prescription

sulfadiazine 400g
Trimethoprim 50g
Appropriate amount of excipients
Made into 1000 tablets

trait

This product is white tablet.

identification

  1. take an appropriate amount of fine powder of this product (about 0.lg of sulfadiazine), add 3ml of 0.4% sodium hydroxide solution and 3ml of water respectively, shake, filter, and take the filtrate and 0.5ml of copper sulfate test solution, that is, a cyan-green precipitate is generated, which changes to a purple-gray color after being placed.
  2. take an appropriate amount of fine powder of this product (about 25mg of trimethoprim), add 5ml of 0.4% sodium hydroxide solution, shake well, add 5ml of chloroform, shake extraction, and take 5ml of chloroform solution and dilute sulfuric acid, after shaking, 2 drops of iodine solution were added to form a brown precipitate in the dilute sulfuric acid layer.
  3. in the chromatogram recorded under the content determination item, the retention time of the two main peaks of the test solution should be consistent with the retention time of the corresponding two main peaks of the control solution.
  4. take an appropriate amount of fine powder of this product (about 50mg equivalent to sulfadiazine) to show the identification reaction of the first aromatic amine (General rule 0301).

examination

  • dissolution of this product, according to the dissolution and release determination method (General 0931 second method), with 0.lmol/L hydrochloric acid solution 1000ml as the dissolution medium, the speed is 75 revolutions per minute, according to the law, after 60 minutes, take 10ml of the solution, filter, take 5ml of the continued filtrate with precision, in a 25ml measuring flask, dilute to the scale with mobile phase, shake well, and measure according to law according to the method under the item of determination containing child, and calculate the dissolution amount of sulfadiazine and trimethoprim in each tablet. The limit shall be 70% of the labeled amount and shall be in accordance with the regulations.
  • others shall be in accordance with the relevant provisions under the item of tablets (General rule 0101).

Content determination

  • determined by HPLC (General 0512) 9
  • chromatographic conditions and system suitability test using eighteen alkyl silane bonded silica gel as filler; Acetonitrile-0.3% ammonium acetate solution (20:80) as mobile phase; The detection wavelength was 220nm. The number of theoretical plates shall not be less than 3000 calculated by trimethoprim peak, and the separation degree between sulfadiazine peak and trimethoprim peak shall meet the requirements.
  • determination of 10 tablets of this product, precision weighing, fine grinding, precision weighing an appropriate amount (equivalent to sulfadiazine 80mg), put in a 100ml measuring flask, add 0.lmol/L sodium hydroxide solution 10ml, shake to dissolve sulfadiazine, then add the appropriate amount of methanol, shake to dissolve trimethoprim, dilute to the scale with methanol, shake, filter, 5ml of the continuous filtrate was accurately measured, placed in a 50ml measuring flask, diluted with mobile phase to the scale, and then shaken to be used as a sample solution. 20 u1 was accurately measured and human liquid chromatograph was injected, record the chromatogram; Take the sulfadiazine control product 80mg and trimethoprim control product 10mg separately, and put them into the same 100ml measuring flask, add 0.lmol/L sodium hydroxide solution 10ml, shake to dissolve sulfadiazine, then add the appropriate amount of methanol, shake to dissolve trimethoprim, dilute to the scale with methanol, shake well, take the appropriate amount with precision, then the mobile phase was quantitatively diluted to prepare a solution containing sulfadiazine 80ug and trimethoprim 10ug per lml, and the same method was used for determination. According to the external standard method to calculate the peak area, that is.

Product Packaging

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery

Usually within3-5 working days after full payment.

transport

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

 

Packing:  
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg); 

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg). 

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg). 

P.S.: we accept packaging customization. 


  
Delivery:   

  1. Stock products are normally shipping within 3 working days.  

  2. For rush delivery, please contact our sales team for particular arrangement. 

Shipping Details: 
  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker. 

  2. Shipping details & shipping documents will be provided and sent by email. 

  3. We keep tracking the shippment until clients well received. 

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

About us

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3. How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.