Product Certification&
Enterprise Certification
Country: China (Mainland)
Business Type:Trading Company
Tel: +86 13910575315
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Tel: +86 19831957301
Mobile: +86 19831957301
Tel: +86 13910575315
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URL: http://hbnq1.com/
Province/state: Hebei
City: Handan
Street: Congtai District, La Defense North
MaxCard:
CAS NO.73-24-5
Pharmaceutical grade(1-50)KilogramPharmaceutical grade(51-99)Kilogram
Our Advantage
Rich Experience
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term.
Quality service
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product.
24 hour service
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage.
High quality
Dedicated to serving customers first, we provide reasonable prices, high quality products.
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is an organic compound commonly abbreviated as TMSA. The following is an introduction to its nature, use, preparation and safety information:
Nature:
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is a colorless liquid with good solubility in water and most organic solvents. Its molecular formula is C9H16O4 and its molecular weight is 188.22g/mol. It has a density of about 0.995 g/mL and a boiling point of about 198-200 ° C.
Use:
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is a commonly used organic synthesis intermediate. It can be used as a substrate, reducing agent and ligand for chiral catalysts. In addition, it can also be used to prepare organic compounds such as drugs, fragrances and dyes.
Method: The preparation of
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER usually involves specific synthetic routes and chemical reactions. A common synthetic method is to obtain (R)-2-methyl-3-methylthiopropionate by oxidation of methyl propyl mercaptan (MPTS), followed by methyl esterification with acetic anhydride to obtain the desired product. Specific synthesis steps and conditions can be adjusted according to needs and experimental conditions.
Safety Information:
(R)-2-METHYLSUCCINIC ACID 4-TERT-BUTYL ESTER is a chemical, so you need to pay attention to safety when using and handling it. It is combustible and should be kept away from fire and flame. Wear protective gloves, goggles and protective clothing during operation. Avoid contact with skin, eyes and respiratory tract. In case of accidental contact, rinse immediately with water and seek medical assistance. In addition, it should be kept away from children and animals, stored in sealed containers, and placed in a cool, dry place.
Density | 1.3795 (rough estimate) |
Melting Point | >360 °C (lit.) |
Boling Point | 238.81°C (rough estimate) |
Flash Point | 220°C |
Water Solubility | 0.5 g/L (20 ºC) |
Solubility | Insoluble in cold water, soluble in boiling water, acid and alkali, slightly soluble in ethanol, insoluble in ether and chloroform |
Vapor Presure | 0.00172mmHg at 25°C |
Appearance | White crystalline powder |
Color | Clear colorless to light yellow |
Odor | Odorless |
Merck | 14,152 |
BRN | 5777 |
pKa | 4.12(at 25℃) |
Storage Condition | 2-8°C |
Stability | Stable. Moisture-sensitive. Incompatible with strong oxidizing agents. |
Sensitive | Easily absorbing moisture |
Refractive Index | 1.7000 (estimate) |
MDL | MFCD00041790 |
Physical and Chemical Properties | Character white fine powder crystal, with strong salty taste. Melting Point: 360~365 ℃ solubility: insoluble in cold water, soluble in boiling water, acid and alkali, slightly soluble in ethanol, insoluble in ether and chloroform. |
Use | For the production of adenosine, ATP, ADP, anti-AIDS drugs and Vitamin B4 and plant growth hormone 6-benzyl adenine |
Authoritative Data Verified Data
pH
take 2.5g of this product, add 50ml of water, boil for 3 minutes, let cool, add water to make up to 50ml, filter, take 10ml of filtrate (the remaining filtrate is ready for use), add bromothymol blue indicator 0.lml and 0.Olmol/L sodium hydroxide solution 0.2ml, the solution is blue, plus 0.01mol/L hydrochloric acid solution 0.4ml, the solution is yellow.
clarity and color of solution
take 0901G of this product, add 50ml of dilute hydrochloric acid to dissolve, check according to law (General rule 0902 and general rule), the solution should be clear and colorless.
chloride
take 0.5g of this product, first burn with small fire to charring, then burn at 500~600°C to Ash completely, let it cool, and check according to law (General rule 0801), not more concentrated (0.01%) than the control solution made from of standard sodium chloride solution.
sulfate
Take 10ml of the filtrate under the pH value and check it according to the law (General rule 0802). Compared with the control solution made of 0.03% of standard potassium sulfate solution, it should not be more concentrated ().
organic impurities
preparation of reference solution the appropriate amount of adenine reference was accurately weighed, heated with an appropriate amount of water to dissolve, allowed to cool, and quantitatively diluted with water to make a solution containing about 0.19mg per 1 ml, respectively, take 3ml into three 100ml measuring bottles, respectively, with O. 1 mol/L hydrochloric acid solution, O. 1 mol/L sodium hydroxide solution, pH 7.0 phosphate buffer [take potassium dihydrogen phosphate 4.54g, dissolve with water and dilute to 500ml, as A solution; Take anhydrous disodium hydrogen phosphate 4.73g, dissolve with water and dilute to 500ml, as B solution. Take 38.9ml of the above solution A and 61.1 ml of the solution B, and shake it well to obtain (if necessary, add the human solution B Dropwise to bring the pH value of the solution to 7.0 )] diluted to the scale, and shake it well.
nitrogen content
take this product about 50mg, precision weighing, inspection according to law (General rule 0704 The first method), according to the dry product calculation, nitrogen content should be 50.2% ~ 53.4%.
loss on drying
Take lg of this product, dry to constant weight at 105°C, and lose no more than 0.5% of weight (General rule 0831).
ignition residue
lg of this product shall be taken for inspection according to law (General rule 0841), and the remaining residue shall not exceed 0.1%.
ammonium salt
Take 2g of this product and check it according to law (General rule 0808). Compared with the standard ammonium chloride solution of 2.0 ml, the control solution made by the same method should not be more concentrated (0.001%).
Heavy metals
The residue left under the item of taking the ignition residue shall not contain more than 10 parts per million of heavy metal when examined by law (General Principles 0821, Law II).
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
Product Packaging:
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage:
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery:
Usually within3-5 working days after full payment.
transport:
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.
Packing:
1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);
2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).
3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
P.S.: we accept packaging customization.
Delivery:
1. Stock products are normally shipping within 3 working days.
2. For rush delivery, please contact our sales team for particular arrangement.
Shipping Details:
1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
2. Shipping details & shipping documents will be provided and sent by email.
3. We keep tracking the shippment until clients well received.
4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.
About us
Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,
We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.
Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization, Keep moving!
FAQ:
1. Are you a trade company or factory
We are a factory with our own trading company.
2.How do you control the quality
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.
3. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
4. Where is your factory located How can I visit the factory
Our factory located in HEBEI, China.
5. Can i get some samples
Yes, we can supply free sample, but the shipping cost be paid by our customers.
6. How to start orders or make payments
Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,
7. How to confirm the Product Quality before placing orders
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
You can send us your product specifications and requests,we will manufacture the products according to your requests.
8. How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
9. How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.