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Hebei Nengqian Chemical Import and Export Co., LTD

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Hebei Nengqian Chemical Import and Export Co., LTD

Country: China (Mainland)

Business Type:Trading Company

Ms.Sunny

Tel: +86 18732968538

Mobile: +86 18732968538

Tel: +86 18732968538

Fax: 4001020630

URL: https://www.nengqianchemical.com/

Province/state: Hebei

City: Handan

Street: Congtai District, La Defense North

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Raloxifene hydrochloride

CAS NO.82640-04-8

  • FOB Price: USD: 1.00-10.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    Pharmaceutical grade(1-50)KilogramPharmaceutical grade(51-99)Kilogram

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Product Details

Keywords

  • Methanone,[6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-,hydrochloride (9CI)
  • 6-Hydroxy-2-(p-hydroxyphenyl)benzo(b)thien-3-yl-p-(2-piperidinoethoxy)phenyl ketone, hydrochloride
  • Bonebay

Quick Details

  • ProName: Raloxifene hydrochloride 82640-0...
  • CasNo: 82640-04-8
  • Molecular Formula: C28H28ClNO4S
  • Appearance: Light yellow
  • Application: The combination of raloxifene and calc...
  • DeliveryTime: 7-10 working days
  • PackAge: In plastic outside weave or according ...
  • Port: port of Qingdao、port of Tianjin
  • ProductionCapacity: 500 Kilogram/Week
  • Purity: >99%
  • Storage: -15°C
  • Transportation: We ship goods via DHL, Fedex, UPS, TNT...
  • LimitNum: 1 Kilogram
  • Grade: Industrial Grade,Food Grade,Pharma Gra...
  • Shelf Life: Two years

Superiority

Our Advantage 

Rich Experience 
Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. 

Quality service 
Company cooperates with research institutes. We strictly control the process of raw materials up to finished product. 
  
24 hour service 
Quick and clear response to customers questions. Warm after sale service, we will help to solve the problems in your usage. 

High quality 
Dedicated to serving customers first, we provide reasonable prices, high quality products. 

 

Details

Our advantage:

1. High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,

and we have stock in there for transferring.

Molecular Formula C28H28ClNO4S
Molar Mass 510.04
Density 1.285g/cm3
Melting Point 250-253°C
Boling Point 687.5°C at 760 mmHg
Flash Point 369.6°C
Solubility DMSO: 28mg/mL, soluble
Vapor Presure 1.56E-19mmHg at 25°C
Appearance solid
Color light yellow
Maximum wavelength(λmax) ['286nm(lit.)']
Merck 14,8098
Storage Condition 2-8°C
Refractive Index 1.654
In vitro study Raloxifene has been shown to be a potent, non-competitive inhibitor of human liver aldehyde dehydrogenase-catalyzed oxidation of phthalazine, vanillin, and nicotine-delta '(5') -imine ions, the Ki values were 0.87 nM, 1.2 nM and 1.4 nM, respectively. Raloxifene is also a noncompetitive inhibitor, inhibiting aldehyde dehydrogenase-catalyzed reduction of hydroxamic acid-containing compounds with an Ki value of 51 nM. Raloxifene activates the TGF β 3 Promoter as a full agonist at nanomolar concentrations, and in transient transfection experiments raloxifene inhibits the expression of estrogen-responsive elements containing the vitellogenin Promoter as a pure estrogen antagonist.
In vivo study In rat femurs, Raloxifene reconstructs bone mineral density and TGF beta 3 mRNA expression. Raloxifene (0.1 mg/kg -10 mg/kg orally for 5 weeks) increased femur and tibia density in ovariectomized rats. In ovariectomized rats, Raloxifene reduces serum cholesterol levels to an ED50 of 0.2 mg/kg. Raloxifene causes a marked lack of estrogenic action in uterine tissue. In ovariectomized rats, Raloxifene blocked osteopenia and changes in bone growth, bone remodeling, and blood cholesterol content, but was less effective in reducing bone formation and did not prevent uterine atrophy.

 

Product Packaging

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 Storage

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Delivery

Usually within3-5 working days after full payment.

transport

EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA

DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service; 

Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;

For high value products, please select air shipping and DHL express for safe;

Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T,, t/t
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
6. Package: Professional packing with professional materials.

 

Packing:  
  1. Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg); 

  2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg). 

  3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg). 

P.S.: we accept packaging customization. 


  
Delivery:   

  1. Stock products are normally shipping within 3 working days.  

  2. For rush delivery, please contact our sales team for particular arrangement. 

Shipping Details: 
  1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker. 

  2. Shipping details & shipping documents will be provided and sent by email. 

  3. We keep tracking the shippment until clients well received. 

  4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently. 

About us

Our company specializes in processing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents,  

We have compalete sales and service team , information feedback vertical integration of a sound marketing network, products are sold throughout the country and exported to South Asia, Europe, America, Africa and other more than 20 countries and regions.  

Companies adhering to the "pursuit of quality, innovation and development" business philosophy, to serve as a foundation, for the survival by the quality, seek development by science and technology, adhere to quilty comes first,fair price,good sense of customer service and responsibility. in the future hebei Nengqian import and export trade Co.,Ltd will always hold "integrity, innovation" business philosophy, to achieve honesty management, on the way of specialization, internationalization,  Keep moving!  

 

FAQ: 
1. Are you a trade company or factory   
We are a  factory with our own trading company.  

2.How do you control the quality   
Our factory is equipped with professional technicians to control quality, out inspectors take sample for testing every 2 hours to ensure the quality of our production. We also accept BV, SGS or any other Third-party inspection.   

3. How long is lead time   
We deliver goods within 3 days for small order, 7-10 days for bulk order.   

4. Where is your factory located  How can I visit the factory   
 Our factory located in HEBEI, China.

5. Can i get some samples  
  Yes, we can supply free sample, but the shipping cost be paid by our customers. 

6. How to start orders or make payments  
  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.Payment by T/T,  

7. How to confirm the Product Quality before placing orders  
  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. 
  You can send us your product specifications and requests,we will manufacture the products according to your requests. 

8. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

9. How do you treat quality complaint

  First of all, our quality control will reduce the quality problem to near zero. If there is a realquality problem caused by us, we will send you free goods for replacement or refund your loss.